Day Jessica, Patel Sandy, Limaye Vidya
Experimental Therapeutics Laboratory, Hanson Institute and Sansom Institute, School of Pharmacy and Medical Science, University of South Australia, Adelaide, SA, Australia; Royal Adelaide Hospital, Adelaide, SA, Australia.
Royal Adelaide Hospital, Adelaide, SA, Australia.
Semin Arthritis Rheum. 2017 Apr;46(5):642-649. doi: 10.1016/j.semarthrit.2016.11.001. Epub 2016 Nov 5.
Magnetic resonance imaging (MRI) is an important tool in the evaluation of neuromuscular disorders. MRI accurately demonstrates muscle oedema, atrophy, subcutaneous pathology and fatty infiltration and also highlights the distribution of muscle involvement. This review examines the role of MRI in evaluation of the idiopathic inflammatory myopathies (IIMs), a heterogeneous group of autoimmune conditions characterised by muscle inflammation and a variety of extra-muscular manifestations. MRI has a clear role in aiding diagnosis of these conditions, guiding muscle biopsy, differentiating subtypes of IIM using a pattern-based approach, and monitoring disease activity in a longitudinal fashion. Whole body MRI is an emerging technique that offers several advantages over regional MRI, but is not currently widely available. We will also consider newer MRI techniques which provide detailed information regarding the metabolism, function and structure of muscle, although their use is restricted to research purposes at present.
磁共振成像(MRI)是评估神经肌肉疾病的重要工具。MRI能准确显示肌肉水肿、萎缩、皮下病变和脂肪浸润,还能突出肌肉受累的分布情况。本综述探讨了MRI在特发性炎性肌病(IIM)评估中的作用,IIM是一组异质性自身免疫性疾病,其特征为肌肉炎症和多种肌肉外表现。MRI在辅助诊断这些疾病、指导肌肉活检、采用基于模式的方法区分IIM亚型以及纵向监测疾病活动方面具有明确作用。全身MRI是一种新兴技术,与局部MRI相比具有多个优势,但目前尚未广泛应用。我们还将考虑更新的MRI技术,这些技术可提供有关肌肉代谢、功能和结构的详细信息,尽管目前其应用仅限于研究目的。