Ashinoff R, Buchness M R, Lim H W
Dermatology Service, New York Veterans Administration Medical Center, New York, NY 10010.
J Am Acad Dermatol. 1989 Nov;21(5 Pt 2):1134-7. doi: 10.1016/s0190-9622(89)70315-7.
A 47-year-old black man with a chronic photocontact dermatitis that evolved into actinic reticuloid was treated with systemically administered PUVA for 15 months. Subsequently an isolated nodule of non-mycosis fungoides T cell lymphoma developed. The use of PUVA may have predisposed this patient to the development of a frank malignancy.
一名47岁的黑人男性患有慢性光接触性皮炎,后发展为光化性类网状细胞增多症,接受了15个月的系统性补骨脂素加紫外线A(PUVA)治疗。随后出现了一例孤立性非蕈样肉芽肿性T细胞淋巴瘤结节。使用PUVA可能使该患者易患明显的恶性肿瘤。