Teltscher J, Silverman R A, Stork J
Department of Dermatology, University Hospitals of Cleveland, OH 44106.
J Am Acad Dermatol. 1989 Nov;21(5 Pt 2):1147-9. doi: 10.1016/s0190-9622(89)70319-4.
In a 4-year-old boy with steriod-resistant syndrome and extreme hyperlipidemia, an intense pruritic papular eruption developed on the trunk, buttocks, and extensor surface of the extremities. Findings from a skin biopsy specimen were consistent with an eruptive xanthoma. The patient was treated with gemfibrozil (Lopid), a low-fat diet, and antihistamines. Within 1 month pruritus diminished, the cutaneous lesions resolved, and serum lipid levels declined.
在一名患有类固醇抵抗综合征和严重高脂血症的4岁男孩中,其躯干、臀部和四肢伸侧出现了剧烈瘙痒的丘疹性皮疹。皮肤活检标本的检查结果与发疹性黄瘤一致。该患者接受了吉非贝齐(诺衡)治疗、低脂饮食和抗组胺药治疗。1个月内瘙痒减轻,皮肤病变消退,血脂水平下降。