Branson R, Naidu K, du Toit C, Rotstein A H, Kiss R, McMillan D, Fooks L, Coombes B K, Vicenzino B
Olympic Park Sports Medicine Centre, Australia.
Victoria House Medical Imaging, MIA Radiology, Australia.
J Sci Med Sport. 2017 Jun;20(6):528-533. doi: 10.1016/j.jsams.2016.10.010. Epub 2016 Oct 29.
To compare three different ultrasound-guided injections for chronic tennis elbow.
Assessor-blinded, randomized controlled comparative trial.
44 patients with clinically diagnosed tennis elbow, confirmed by Doppler ultrasound, received under ultrasound guidance, a single corticosteroid injection (n=14), or two injections (separated by 4 weeks) of either autologous blood (n=14) or polidocanol (n=16). Clinical and ultrasound examination was performed at baseline, 4, 12 and 26 weeks.
Complete recovery or much improvement was greater for corticosteroid injection than autologous blood and polidocanol at 4 weeks (p<0.001, number needed to treat 1 (95% CI 1-2)). In contrast, at 26 weeks corticosteroid was significantly worse than polidocanol (p=0.004, number needed to harm 2 (1-6)). Recurrence after corticosteroid injection was significantly higher than autologous blood or polidocanol (p=0.007, number needed to harm 2 (1-4)). Corticosteroid injection produced greater reduction in tendon thickness and vascularity than autologous blood at 4 weeks only. Compared to autologous blood, polidocanol reduced tendon thickness at 4 and 12 weeks and reduced echogenicity and hyperaemia after 12 or 26 weeks respectively.
Injections of corticosteroid cannot be recommended over polidocanol or autologous blood, because despite beneficial short-term effect there were inferior long-term effects. Whether polidocanol or autologous blood injections are effective is unknown, especially as their global effect profiles are not unlike previously reported for wait-and-see.
比较三种不同的超声引导下注射疗法治疗慢性网球肘的效果。
评估者盲法、随机对照比较试验。
44例经临床诊断为网球肘且经多普勒超声确诊的患者,在超声引导下接受单次皮质类固醇注射(n = 14),或接受两次注射(间隔4周),分别为自体血注射(n = 14)或聚多卡醇注射(n = 16)。在基线、4周、12周和26周时进行临床和超声检查。
在4周时,皮质类固醇注射组的完全恢复或明显改善情况优于自体血注射组和聚多卡醇注射组(p<0.001,需治疗人数为1(95%可信区间1 - 2))。相比之下,在26周时,皮质类固醇注射组明显差于聚多卡醇注射组(p = 0.004,危害需治疗人数为2(1 - 6))。皮质类固醇注射后的复发率明显高于自体血注射组或聚多卡醇注射组(p = 0.007,危害需治疗人数为2(1 - 4))。仅在4周时,皮质类固醇注射使肌腱厚度和血管化程度的降低幅度大于自体血注射。与自体血相比,聚多卡醇在4周和12周时降低了肌腱厚度,在12周或26周后分别降低了回声性和充血情况。
不推荐使用皮质类固醇注射而非聚多卡醇或自体血注射,因为尽管皮质类固醇注射有短期益处,但长期效果较差。聚多卡醇或自体血注射是否有效尚不清楚,尤其是它们的总体效果特征与先前报道的观察等待情况并无不同。