Stoopen-Rometti M, Encinas-Escobar E R, Ramirez-Carmona C R, Wolpert-Barraza E, Kimura-Hayama E, Sosa-Lozano L A, Favila R, Kimura-Fujikami Y, Saavedra-Abril J A, Loaeza-Del Castillo A
Departamento de Imagen, C.T. Scanner Lomas Altas, Ciudad de México, México.
Curso Universitario de Radiología, C.T. Scanner, Instituto Nacional de Cardiología Ignacio Chávez, Universidad Nacional Autónoma de México, Ciudad de México, México.
Rev Gastroenterol Mex. 2017 Jan-Mar;82(1):32-45. doi: 10.1016/j.rgmx.2016.06.001. Epub 2017 Jan 12.
The presence of liver fibrosis is the common denominator in numerous chronic liver diseases that can progress to fibrosis and hepatocellular carcinoma. Most important, with respect to frequency, are viral hepatitis and non-alcoholic fatty liver disease, the prevalence of which is increasing in epidemic proportions. Liver biopsy, albeit imperfect, continues to be the criterion standard, but in many clinical situations tends to be replaced with noninvasive imaging methods.
The aim of the present article was to describe our imaging department experience with magnetic resonance elastography and to analyze and discuss recently published results in gastroenterology, hepatology, and radiology from other authors in the literature, complemented with a PubMed search covering the last 10 years.
Magnetic resonance elastography is an efficacious, noninvasive method with results that are concordant with liver biopsy. It is superior to ultrasound elastography because it evaluates a much greater volume of hepatic tissue and shows the often heterogeneous lesion distribution. The greatest advantage of the magnetic resonance protocol described is the fact that it quantifies fibrosis, fat content, and iron content in the same 25min examination specifically directed for that purpose, resulting in a favorable cost-benefit ratio for the patient and/or institution.
肝纤维化的存在是众多慢性肝病的共同特征，这些慢性肝病可进展为纤维化和肝细胞癌。就发病率而言，最重要的是病毒性肝炎和非酒精性脂肪性肝病，其患病率正呈流行比例上升。肝活检尽管并不完美，但仍然是标准准则，但在许多临床情况下，它往往被非侵入性成像方法所取代。
本文旨在描述我们影像科在磁共振弹性成像方面的经验，并分析和讨论文献中其他作者最近在胃肠病学、肝病学和放射学方面发表的结果，并辅以过去10年的PubMed搜索。
磁共振弹性成像是一种有效的非侵入性方法，其结果与肝活检结果一致。它优于超声弹性成像，因为它评估的肝组织体积大得多，并且显示出病变分布通常不均匀。所描述的磁共振检查方案的最大优点是，它可以在专门为此目的进行的25分钟检查中同时量化纤维化、脂肪含量和铁含量，从而为患者和/或机构带来良好的成本效益比。
