Department of Experimental Psychology, Utrecht University, Utrecht, The Netherlands.
Department of Experimental Psychology, Utrecht University, Utrecht, The Netherlands.
Trends Cogn Sci. 2017 Feb;21(2):125-136. doi: 10.1016/j.tics.2016.11.005. Epub 2017 Jan 12.
Millions of women worldwide use oral contraceptives ('the pill'; OCs), often starting at a pubertal age when their brains are in a crucial developmental stage. Research into the social-emotional effects of OCs is of utmost importance. In this review, we provide an overview of studies that have emerged over the past decade investigating how OCs, and their main ingredients estradiol (E) and progesterone (P), influence social-emotional behaviors and underlying brain functions. Based on this overview, we present a heuristic model that postulates that OCs modulate core social-emotional behaviors and brain systems. Research domains and challenges for the future, as well as implications, are discussed.
全世界有数百万人使用口服避孕药（“避孕药”；OCs），通常在青春期开始时服用，此时她们的大脑正处于关键的发育阶段。研究 OC 对社会情感的影响至关重要。在这篇综述中，我们概述了过去十年中出现的研究，这些研究调查了 OC 及其主要成分雌二醇（E）和孕酮（P）如何影响社会情感行为和大脑的基础功能。在此基础上，我们提出了一个启发式模型，假设 OC 调节核心的社会情感行为和大脑系统。讨论了未来的研究领域和挑战，以及所涉及的问题。
