Park Hyun Jong, Kim You Shin, Yoon Tae Ki, Lee Woo Sik
Department of Obstetrics and Gynecology, Fertility Center of CHA Gumi Medical Center, CHA University, Gumi, Korea.
Department of Obstetrics and Gynecology, Fertility Center of CHA Gangnam Medical Center, CHA University, Seoul, Korea.
Clin Exp Reprod Med. 2016 Dec;43(4):185-192. doi: 10.5653/cerm.2016.43.4.185. Epub 2016 Dec 26.
Chronic endometritis (CE) is a condition involving the breakdown of the peaceful co-existence between microorganisms and the host immune system in the endometrium. A majority of CE cases produce no noticeable signs or mild symptoms, and the prevalence rate of CE has been found to be approximately 10%. Gynecologists and pathologists often do not focus much clinical attention on CE due to the time-consuming microscopic examinations necessary to diagnose CE, its mild clinical manifestations, and the benign nature of the disease. However, the relationship between CE and infertility-related conditions such as repeated implantation failure and recurrent miscarriage has recently emerged as an area of inquiry. In this study, we reviewed the literature on the pathophysiology of CE and how it may be associated with infertility, as well as the literature regarding the diagnosis and treatment of CE. In addition, we discuss the value of hysteroscopic procedures in the diagnosis and treatment of CE.
慢性子宫内膜炎（CE）是一种涉及子宫内膜中微生物与宿主免疫系统之间和谐共生关系被破坏的病症。大多数CE病例没有明显体征或仅有轻微症状，且CE的患病率约为10%。由于诊断CE需要耗时的显微镜检查、其临床表现轻微以及疾病的良性性质，妇科医生和病理学家通常不太关注CE。然而，CE与反复种植失败和复发性流产等不孕症相关病症之间的关系最近已成为一个研究领域。在本研究中，我们回顾了关于CE病理生理学及其与不孕症可能关联的文献，以及关于CE诊断和治疗的文献。此外，我们还讨论了宫腔镜手术在CE诊断和治疗中的价值。
