Protsenko Yu L, Balakin A A, Kuznetsov D A, Kursanov A G, Lisin R V, Mukhlynina E A, Lookin O N
Institute of Immunology and Physiology, Ural Division of Russian Academy of Sciences, Ekaterinburg, Russia.
B. N. Yeltsin Ural Federal University, Ekaterinburg, Russia.
Bull Exp Biol Med. 2017 Jan;162(3):303-305. doi: 10.1007/s10517-017-3600-x. Epub 2017 Jan 14.
Sex differences in the morphogenesis and adaptation of the mechanisms controlling myocardium contractility during physiological and pathological hypertrophy of the right ventricle were demonstrated in mature rats. The study revealed sex-dependent effects of physiological and pathological cardiac hypertrophy on the coefficient of variation of the cardiomyocyte diameter, length-dependent control of the contractile force, and the maximum velocity of isotonic shortening.
在成年大鼠中证实了右心室生理性和病理性肥大过程中心肌收缩力控制机制的形态发生和适应性方面的性别差异。该研究揭示了生理性和病理性心脏肥大对心肌细胞直径变异系数、收缩力的长度依赖性控制以及等张收缩最大速度的性别依赖性影响。
