基于频域光学相干断层扫描技术的跨突触性视网膜变性进展情况
Progression of Transsynaptic Retinal Degeneration With Spectral-Domain Optical Coherence Tomography.
作者信息
Schwartz Stephen G, Monroig Armando, Flynn Harry W
机构信息
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL.
出版信息
Am J Ophthalmol Case Rep. 2017 Apr;5:67-72. doi: 10.1016/j.ajoc.2016.12.010. Epub 2016 Dec 14.
PURPOSE
To illustrate the progression of retrograde transsynaptic retinal degeneration using spectral- domain optical coherence tomography (SD-OCT).
OBSERVATIONS
A 60 year-old man with a stroke was followed over a 17-month period using SD-OCT of the macula, ganglion cell layer (GCC), and retinal nerve fiber layer. Transsynaptic retinal degeneration progressed over this time.
CONCLUSIONS AND IMPORTANCE
Retrograde transsynaptic retinal degeneration may occur in patients with homonymous visual field loss caused by post-geniculate neurologic disease. This is best detected as homonymous thinning of the retina, corresponding to the pattern of visual field loss, using SD-OCT of the GCC and macula. The retinal changes occur at a variable time following the onset of neurologic disease.
目的
利用频域光学相干断层扫描（SD - OCT）阐述逆行性跨突触视网膜变性的进展情况。
观察结果
一名60岁中风男性患者在17个月的时间里接受了黄斑、神经节细胞层（GCC）和视网膜神经纤维层的SD - OCT检查。在此期间，跨突触视网膜变性不断进展。
结论与意义
膝状体后神经疾病导致的同侧视野缺损患者可能会发生逆行性跨突触视网膜变性。利用GCC和黄斑的SD - OCT检查，最容易检测到与视野缺损模式相对应的视网膜同侧变薄。视网膜变化在神经疾病发作后的不同时间出现。
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