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分次二氧化碳激光成功治疗创伤性甲营养不良及相关甲胬肉:病例报告及文献综述

Successful Treatment of Traumatic Onychodystrophy and Associated Pterygium Unguis With Fractionated Carbon Dioxide Laser: Case Report and Review of the Literature.

作者信息

Ho Derek, Mamalis Andrew, Jagdeo Jared

出版信息

J Drugs Dermatol. 2016 Nov 1;15(11):1461-1464.

PMID:28095564
Abstract

Onychodystrophy is a common, chronic malformation of the nail that is aesthetically displeasing and can signi cantly impact patient quality-of-life. Onychodystrophy can be associated with pterygium unguis that contributes to pain and appears as a V-shaped exten- sion of the proximal nail fold skin. Treatment options are limited, and topical or intralesional corticosteroids have minimal ef cacy and cause signi cant patient discomfort. Surgical revision of onychodystrophy is complex, and symptomatic or aesthetic improvements are difficult to achieve. There is limited published literature on laser treatment of noninfectious onychodystrophy or associated pterygium unguis. We present a case of a 68-year-old man with a 10-year history of painful traumatic onychodystrophy with associated pterygium unguis, who was successfully treated after three treatments of fractionated carbon dioxide (CO2) laser. Additionally, we review the medical literature on laser treatment of noninfectious onychodystrophy and pterygium unguis. To our knowledge, this is the first reported successful treatment of painful traumatic onychodystrophy and associated pterygium unguis using fractionated CO2 laser. We hope clinicians consider this treatment modality to relieve pain and improve aesthetics associated with traumatic onychodystrophy and associated pterygium unguis. We envision additional research investigating the mechanism of action of fractionated CO2 laser may con rm this treatment option for the management of traumatic onychodystrophy and associated pterygium unguis. J Drugs Dermatol. 2016;15(11):1461-1464..

摘要

甲营养不良是一种常见的慢性指甲畸形,在美观上令人不悦,并且会显著影响患者的生活质量。甲营养不良可能与甲胬肉有关,甲胬肉会导致疼痛,表现为近端甲皱襞皮肤呈V形延伸。治疗选择有限,外用或病损内注射皮质类固醇疗效甚微,且会给患者带来明显不适。甲营养不良的手术矫正很复杂,难以实现症状改善或美观改善。关于激光治疗非感染性甲营养不良或相关甲胬肉的已发表文献有限。我们报告一例68岁男性,有10年疼痛性创伤性甲营养不良伴相关甲胬肉病史,在接受三次分次二氧化碳(CO2)激光治疗后成功治愈。此外,我们回顾了关于激光治疗非感染性甲营养不良和甲胬肉的医学文献。据我们所知,这是首次报道使用分次CO2激光成功治疗疼痛性创伤性甲营养不良及相关甲胬肉。我们希望临床医生考虑这种治疗方式,以缓解与创伤性甲营养不良及相关甲胬肉相关的疼痛并改善美观。我们设想进一步研究分次CO2激光的作用机制,可能会证实这种治疗方案可用于管理创伤性甲营养不良及相关甲胬肉。《皮肤药物学杂志》。2016年;15(11):1461 - 1464。

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