Kraeva Ekaterina, Ho Derek, Jagdeo Jared
J Drugs Dermatol. 2016 Nov 1;15(11):1465-1468.
Rhinophyma, a late complication of rosacea (phymatous subtype), is a chronic, progressive dermatological condition. The classic pre- sentation of rhinophyma is nodular, thickened skin over the distal nose, and is often accompanied by underlying erythema secondary to in ammation. Due to the unpleasant aesthetic and dis guring appearance, rhinophyma may be associated with a signi cant nega- tive psychosocial impact, resulting in decreased patient quality-of-life. Treatment of rhinophyma is challenging as topical and systemic pharmacotherapies have shown limited ef cacy. We present a case of a 39-year-old African-American male with long-standing, mild rhinophyma who was successfully treated with two sessions of fractionated carbon dioxide (CO2) laser. We also review the medical literature on fractionated CO2 laser treatment of rhinophyma. To the best of our knowledge, this is the rst report of successful treat- ment of rhinophyma using fractionated CO2 laser in an African-American man (Fitzpatrick VI). We believe that fractionated CO2 laser may be a safe and ef cacious treatment modality for rhinophyma in skin of color patients (Fitzpatrick IV-VI) and early intervention with fractionated CO2 laser to prevent rhinophyma worsening may yield better results than late intervention. J Drugs Dermatol. 2016;15(11):1465-1468..
酒渣鼻赘生物是酒渣鼻（肥大性亚型）的晚期并发症，是一种慢性、进行性皮肤病。酒渣鼻赘生物的典型表现为鼻尖部皮肤结节状增厚，常伴有炎症继发的红斑。由于外观不佳且有损容貌，酒渣鼻赘生物可能会对患者心理社会产生显著负面影响，导致患者生活质量下降。酒渣鼻赘生物的治疗具有挑战性，因为局部和全身药物治疗效果有限。我们报告一例39岁非裔美国男性，患有长期轻度酒渣鼻赘生物，经两次分次二氧化碳（CO2）激光治疗成功治愈。我们还回顾了关于分次CO2激光治疗酒渣鼻赘生物的医学文献。据我们所知，这是首例在非裔美国男性（菲茨帕特里克VI型）中使用分次CO2激光成功治疗酒渣鼻赘生物的报告。我们认为，分次CO2激光可能是治疗有色人种患者（菲茨帕特里克IV - VI型）酒渣鼻赘生物的一种安全有效的治疗方式，早期采用分次CO2激光干预以防止酒渣鼻赘生物恶化可能比晚期干预效果更好。《皮肤药物学杂志》。2016年；15（11）：1465 - 1468。
