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伦敦塔计分系统与常模数据的比较研究

A Comparative Study of Tower of London Scoring Systems and Normative Data.

作者信息

Michalec Jiri, Bezdicek Ondrej, Nikolai Tomas, Harsa Pavel, Jech Robert, Silhan Petr, Hyza Martin, Ruzicka Evzen, Shallice Tim

机构信息

Department of Psychiatry, First Faculty of Medicine and General University Hospital in Prague, Charles University in Prague, Prague, Czech Republic.

Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine and General University Hospital in Prague, Charles University in Prague, Prague, Czech Republic.

出版信息

Arch Clin Neuropsychol. 2017 May 1;32(3):328-338. doi: 10.1093/arclin/acw111.

Abstract

OBJECTIVE

Tower of London (ToL) is a planning ability task that includes multiple versions. The original ToL was developed by Shallice together with two scoring systems (ToL-SS). Another two ToL-SS were proposed by Anderson et al. and Krikorian et al. The purpose of this study is to provide normative data for four ToL-SS and explore the effects of demographic variables on ToL performance. Furthermore, we aimed to determine the discriminative validity of these ToL-SS in clinical samples.

METHOD

Four groups were included in the study: a normative sample of healthy adults (HC; n = 298); patients with Parkinson's disease with mild cognitive impairment (PD-MCI; n = 52) and without cognitive impairment (PD-ND; n = 57); and patients with schizophrenia (SCH; n = 28). The effects of demographic variables on ToL-SS were examined in the HC group. Between-groups comparisons of ToL-SS were conducted using regression analysis with dummy codes.

RESULTS

All four ToL-SS were not significantly affected by age, whereas the effect of gender and education is not consistent. ToL-SS significantly (p < .05) differentiate HC from PD-MCI and SCH. Cohen's effect size coefficients d range from 0.68 to 1.29. Internal consistency coefficients (Cronbach's α) of ToL-SS range from 0.33 to 0.60.

CONCLUSIONS

Despite poor to questionable internal consistency of ToL-SS, the discriminative validity and clinical utility for assessing planning deficits in PD-MCI and SCH are high. This study provides normative standards for all four ToL-SS on an adult population for use in clinical practice.

摘要

目的

伦敦塔(ToL)是一项规划能力任务,有多个版本。最初的ToL由沙利斯开发,并配有两种评分系统(ToL - SS)。安德森等人和克里科里安等人又提出了另外两种ToL - SS。本研究的目的是为四种ToL - SS提供常模数据,并探讨人口统计学变量对ToL表现的影响。此外,我们旨在确定这些ToL - SS在临床样本中的区分效度。

方法

本研究纳入四组:健康成年人常模样本(HC;n = 298);患有轻度认知障碍的帕金森病患者(PD - MCI;n = 52)和无认知障碍的帕金森病患者(PD - ND;n = 57);以及精神分裂症患者(SCH;n = 28)。在HC组中检验人口统计学变量对ToL - SS的影响。使用虚拟编码的回归分析对ToL - SS进行组间比较。

结果

所有四种ToL - SS均未受到年龄的显著影响,而性别和教育程度的影响并不一致。ToL - SS能显著(p <.05)区分HC与PD - MCI和SCH。科恩效应量系数d范围为0.68至1.29。ToL - SS的内部一致性系数(克朗巴哈α系数)范围为0.33至0.60。

结论

尽管ToL - SS的内部一致性较差或存在疑问,但其在评估PD - MCI和SCH的规划缺陷方面的区分效度和临床实用性较高。本研究为所有四种ToL - SS在成年人群中提供了用于临床实践的常模标准。

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