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一项重症哮喘标准化临床与管理计划可缩短重症哮喘治疗时长。

A Critical Asthma Standardized Clinical and Management Plan Reduces Duration of Critical Asthma Therapy.

作者信息

Wong Jackson, Agus Michael S D, Graham Dionne A, Melendez Elliot

机构信息

Divisions of Medicine Critical Care and.

Institute for Relevant Clinical Data Analytics.

出版信息

Hosp Pediatr. 2017 Feb;7(2):79-87. doi: 10.1542/hpeds.2016-0087. Epub 2017 Jan 17.

Abstract

BACKGROUND AND OBJECTIVE

Reduction of critical asthma management time can reduce intensive care utilization. The goal of this study was to determine whether a Critical Asthma Standardized Clinical Assessment and Management Plan (SCAMP) can decrease length of critical asthma management time.

METHODS

This retrospective study compared critical asthma management times in children managed before and after implementation of a Critical Asthma SCAMP. The SCAMP used an asthma severity score management scheme to guide stepwise escalation and weaning of therapies. The SCAMP guided therapy until continuous albuterol nebulization (CAN) was weaned to intermittent albuterol every 2 hours (q2h). Because the SCAMP was part of a quality improvement initiative in which all patients received a standardized therapy, informed consent was waived. The study was conducted in Medicine ICU and Intermediate Care Units in a tertiary care freestanding children's hospital. Children ≥2 years of age who had CAN initiated in the emergency department and were admitted to the Division of Medicine Critical Care with status asthmaticus were included. The time to q2h dosing from initiation of CAN was compared between the baseline and SCAMP cohorts. Adverse events were compared. The Mann-Whitney test was used for analysis; P values <.05 were considered statistically significant.

RESULTS

There were 150 baseline and 123 SCAMP patients eligible for analysis. There was a decrease in median time to q2h dosing after the SCAMP (baseline, 21.6 hours [interquartile range, 3.2-32.3 hours]; SCAMP, 14.2 hours [interquartile range, 9.0-23.1 hours]; P < .01). There were no differences in adverse events or readmissions.

CONCLUSIONS

A Critical Asthma SCAMP was effective in decreasing time on continuous albuterol.

摘要

背景与目的

缩短重症哮喘管理时间可减少重症监护的使用。本研究的目的是确定重症哮喘标准化临床评估与管理计划(SCAMP)是否能缩短重症哮喘管理时间。

方法

这项回顾性研究比较了实施重症哮喘SCAMP前后儿童的重症哮喘管理时间。SCAMP采用哮喘严重程度评分管理方案来指导治疗的逐步升级和减量。SCAMP指导治疗直至持续沙丁胺醇雾化(CAN)减至每2小时一次的间歇沙丁胺醇(q2h)。由于SCAMP是质量改进计划的一部分,所有患者均接受标准化治疗,因此无需知情同意。该研究在一家独立的三级儿童医院的内科重症监护病房和中级护理病房进行。纳入年龄≥2岁、在急诊科开始接受CAN治疗并因哮喘持续状态入住内科重症监护科的儿童。比较基线队列和SCAMP队列从开始CAN治疗到q2h给药的时间。比较不良事件。采用Mann-Whitney检验进行分析;P值<.05被认为具有统计学意义。

结果

有150例基线患者和123例SCAMP患者符合分析条件。SCAMP实施后,至q2h给药的中位时间缩短(基线,21.6小时[四分位间距,3.2 - 32.3小时];SCAMP,14.2小时[四分位间距,9.0 - 23.1小时];P <.01)。不良事件或再入院率无差异。

结论

重症哮喘SCAMP可有效缩短持续使用沙丁胺醇的时间。

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