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本文引用的文献

1
Psychiatric and cognitive manifestations of hypothyroidism.甲状腺功能减退的精神和认知表现。
Curr Opin Endocrinol Diabetes Obes. 2014 Oct;21(5):377-83. doi: 10.1097/MED.0000000000000089.
2
Is Thyroid Autoimmunity per se a Determinant of Quality of Life in Patients with Autoimmune Hypothyroidism?甲状腺自身免疫是否是自身免疫性甲状腺功能减退症患者生活质量的决定因素?
Eur Thyroid J. 2012 Oct;1(3):186-92. doi: 10.1159/000342623. Epub 2012 Sep 29.
3
Psychometric properties of the Iranian interview-administered version of the World Health Organization's Quality of Life Questionnaire (WHOQOL-BREF): a population-based study.世界卫生组织生活质量问卷(WHOQOL - BREF)伊朗访谈管理版的心理测量特性:一项基于人群的研究。
BMC Health Serv Res. 2008 Mar 21;8:61. doi: 10.1186/1472-6963-8-61.
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Quality of life in hepatitis C.丙型肝炎患者的生活质量
Liver Int. 2006 Sep;26(7):755-65. doi: 10.1111/j.1478-3231.2006.01331.x.
5
Health-related Quality of Life, depression and anxiety in thyroid cancer patients.甲状腺癌患者的健康相关生活质量、抑郁和焦虑
Qual Life Res. 2006 May;15(4):695-703. doi: 10.1007/s11136-005-3689-7.
6
Subclinical hypothyroidism increases the risk for depression in the elderly.亚临床甲状腺功能减退会增加老年人患抑郁症的风险。
Arch Gerontol Geriatr. 2007 Jan-Feb;44(1):21-8. doi: 10.1016/j.archger.2006.02.001. Epub 2006 May 5.
7
Quality of life in longterm exogenous subclinical hyperthyroidism and the effects of restoration of euthyroidism, a randomized controlled trial.长期外源性亚临床甲状腺功能亢进症患者的生活质量及甲状腺功能恢复正常的影响:一项随机对照试验
Clin Endocrinol (Oxf). 2006 Mar;64(3):284-91. doi: 10.1111/j.1365-2265.2006.02458.x.
8
[Autoimmune thyroid disease and associated diseases].[自身免疫性甲状腺疾病及相关疾病]
Srp Arh Celok Lek. 2005 Oct;133 Suppl 1:84-7. doi: 10.2298/sarh05s1084l.
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Instruments used in measuring symptoms, health status and quality of life in hypothyroidism: a systematic qualitative review.
Clin Endocrinol (Oxf). 2005 Dec;63(6):617-24. doi: 10.1111/j.1365-2265.2005.02381.x.
10
Depression, anxiety, health-related quality of life, and disability in patients with overt and subclinical thyroid dysfunction.显性和亚临床甲状腺功能障碍患者的抑郁、焦虑、健康相关生活质量及残疾情况
Arch Med Res. 2006 Jan;37(1):133-9. doi: 10.1016/j.arcmed.2005.05.008.

设拉子医科大学莫塔哈里诊所甲状腺功能减退患者与正常人生活质量和心理健康状况的比较

A Comparison between the Quality of Life and Mental Health of Patients with Hypothyroidism and Normal People Referred to Motahari Clinic of Shiraz University of Medical Sciences.

作者信息

Rakhshan Mahnaz, Ghanbari Alireza, Rahimi Atefeh, Mostafavi Issac

机构信息

Community Based Psychiatric Care Research Center, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.

Student Research Committee, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Int J Community Based Nurs Midwifery. 2017 Jan;5(1):30-37.

PMID:28097176
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5219563/
Abstract

BACKGROUND

Hypothyroidism is a condition caused by a decrease in the thyroid gland hormones. This disease is very common at all age ranges. Regarding its long term therapeutic procedure, this disease can affect the quality of life and the mental health of the patients. The present study aimed to compare the quality of life and mental health in hypothyroid patients and normal people.

METHODS

This descriptive-analytic investigation was performed using convenience sampling on 95 patients with hypothyroidism and 95 normal cases referring to Motahari clinic between October 2014 and August 2015. Data were collected through General Health Questionnaire (consisted of 4 fields; physical signs, anxiety, social function disorder, depression) and Quality of life Questionnaires. Data were analyzed using Independent t- test, Pearson correlation coefficient and Variance analysis. P-values<0.05 were considered as significant.

RESULTS

Both control (normal) and test (patient) groups were matched in demographic characteristics in this study (P>0.001). The results showed that there was no significant difference between the quality of life of patients and that of the normal people (test and control groups) (P>0.001). But the comparison of mental health level of patients (59.70) and normal people (48.68) showed a significant difference at all aspects (P<0.001).

CONCLUSION

Considering and improving the mental health status of such patients can be positively effective in their treatment procedure. Considering this key point in a country like Iran with rich religious backgrounds can be useful in designing self-care and therapeutic programs and even for all people.

摘要

背景

甲状腺功能减退症是一种由甲状腺激素分泌减少引起的病症。这种疾病在各个年龄段都很常见。就其长期治疗过程而言,该疾病会影响患者的生活质量和心理健康。本研究旨在比较甲状腺功能减退症患者与正常人的生活质量和心理健康状况。

方法

本描述性分析研究采用便利抽样法,对2014年10月至2015年8月期间到莫塔哈里诊所就诊的95例甲状腺功能减退症患者和95例正常对照者进行研究。通过一般健康问卷(包括4个方面:身体体征、焦虑、社会功能障碍、抑郁)和生活质量问卷收集数据。使用独立t检验、Pearson相关系数和方差分析对数据进行分析。P值<0.05被认为具有统计学意义。

结果

在本研究中,对照组(正常组)和试验组(患者组)在人口统计学特征方面相匹配(P>0.001)。结果显示,患者与正常人(试验组和对照组)的生活质量之间无显著差异(P>0.001)。但是,患者(59.70)与正常人(48.68)心理健康水平的比较在各个方面均显示出显著差异(P<0.001)。

结论

关注并改善此类患者的心理健康状况对其治疗过程可能具有积极效果。在像伊朗这样具有丰富宗教背景的国家,考虑到这一关键点对于设计自我护理和治疗方案甚至对所有人都可能是有益的。