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定制3D打印的患者特异性脊柱植入物在C1/2关节固定术中的应用。

Application of a 3D custom printed patient specific spinal implant for C1/2 arthrodesis.

作者信息

Phan Kevin, Sgro Alessandro, Maharaj Monish M, D'Urso Paul, Mobbs Ralph J

机构信息

Neuro Spine Surgery Research Group (NSURG), Sydney, Australia;; Faculty of Medicine, University of Sydney, Sydney, Australia.

Neuro Spine Surgery Research Group (NSURG), Sydney, Australia.

出版信息

J Spine Surg. 2016 Dec;2(4):314-318. doi: 10.21037/jss.2016.12.06.

Abstract

The study aims to describe a three-dimensional printed (3DP) posterior fixation implant used for C1/C2 fusion in a 65-year-old female. Spinal fusion remains a common intervention for a range of spinal pathologies including degenerative disc and facet disease when conservative methods are unsuccessful. However, fusion devices are not always entirely efficacious in providing the desired fixation, and surgeons rely on 'off the shelf' implants which may not provide an anatomical fit to address the particular pathology. 3DP refers to a process where three-dimensional objects are created through successive layering of material, so called 'additive manufacturing'. Although this technology enables accurate fabrication of patient-specific orthopaedic and spinal implants, literature on its utilization in this regard is rare. A 65-year-old female, with severe facet arthropathy at the C1/C2 level, osteophyte formation and impingement of the exiting C2 nerve root underwent a C1/C2 posterior fusion and rhizolysis of the C2 nerve roots. A custom posterior fixation implant was designed and on-laid over the C2 spinous process and lamina, with screw holes made to a depth and angulation that was pre-calculated based on the preoperative CT based 3D modelling. The patient had an uneventful recovery and reported a significant reduction in occipital neuralgia and sub-occipital pain and 2-month follow-up. We report the first case of a customized 3DP spinal prosthesis for posterior C1/C2 fusion. The implant added significant value reducing the overall time of the procedure, and safety with a reduced risk of neurovascular compromise.

摘要

该研究旨在描述一种用于一名65岁女性C1/C2融合的三维打印(3DP)后路固定植入物。当保守治疗方法无效时,脊柱融合仍然是治疗一系列脊柱疾病(包括椎间盘退变和小关节疾病)的常见干预措施。然而,融合装置在提供所需固定方面并不总是完全有效,外科医生依赖“现成的”植入物,而这些植入物可能无法提供适合特定病理情况的解剖学匹配。3DP是指通过材料的连续分层创建三维物体的过程,即所谓的“增材制造”。尽管这项技术能够精确制造针对患者的骨科和脊柱植入物,但关于其在这方面应用的文献却很少。一名65岁女性,C1/C2水平患有严重的小关节病、骨赘形成以及C2神经根出口受压,接受了C1/C2后路融合和C2神经根松解术。设计了一种定制的后路固定植入物,并放置在C2棘突和椎板上,根据术前基于CT的三维建模预先计算出螺钉孔的深度和角度。患者恢复顺利,在2个月的随访中,枕神经痛和枕下疼痛明显减轻。我们报告了首例用于C1/C2后路融合的定制3DP脊柱假体病例。该植入物具有显著价值,减少了手术的总时间,并提高了安全性,降低了神经血管损伤的风险。

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