Firoozabadi Reza, Alton Timothy, Sagi Henry Claude
From the Department of Orthopaedics, University of Washington Hospitals, Seattle, WA.
J Am Acad Orthop Surg. 2017 Feb;25(2):117-124. doi: 10.5435/JAAOS-D-15-00366.
Heterotopic ossification (HO) is a common complication of the surgical treatment of acetabular fractures. HO is the formation of trabecular bone in soft tissues where bone does not usually occur. Over the last decade, many risk factors have been identified for HO after surgical fixation of acetabular fractures; however, prophylaxis and treatment of this condition are controversial. Potential preventive measures range from NSAIDs to external beam irradiation, but recent studies have questioned the utility of these measures. The Brooker classification system, which has been correlated with patient function and outcomes, is most commonly used to describe HO severity. Advances will assist in the diagnosis, prevention, and management of HO as well as the assessment of risk factors that could affect outcomes.
异位骨化（HO）是髋臼骨折手术治疗的常见并发症。HO是在通常不会形成骨的软组织中形成小梁骨。在过去十年中，已确定了髋臼骨折手术固定后发生HO的许多风险因素；然而，这种情况的预防和治疗仍存在争议。潜在的预防措施从非甾体抗炎药到外照射，但最近的研究对这些措施的效用提出了质疑。与患者功能和预后相关的布鲁克分类系统最常用于描述HO的严重程度。研究进展将有助于HO的诊断、预防和管理，以及评估可能影响预后的风险因素。
