单侧视网膜分支静脉阻塞患者视乳头周围脉络膜厚度显著降低。
SIGNIFICANT REDUCTION OF PERIPAPILLARY CHOROIDAL THICKNESS IN PATIENTS WITH UNILATERAL BRANCH RETINAL VEIN OCCLUSION.
作者信息
Kang Hae Min, Choi Jeong Hoon, Koh Hyoung Jun, Lee Christopher Seungkyu, Lee Sung Chul
机构信息
Department of Ophthalmology, Catholic Kwandong University College of Medicine, International St. Mary's Hospital, Incheon, Republic of Korea.
Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Republic of Korea.
出版信息
Retina. 2018 Jan;38(1):72-78. doi: 10.1097/IAE.0000000000001495.
PURPOSE
To evaluate changes in peripapillary choroidal thickness in patients with branch retinal vein occlusion (BRVO) over 12 months, using spectral-domain optical coherence tomography with enhanced depth imaging.
METHODS
This retrospective, interventional case series included 20 treatment-naive patients with unilateral BRVO with at least 12 months follow-up. The peripapillary choroidal thickness was measured over 12 months.
RESULTS
In BRVO-affected eyes, the mean peripapillary choroidal thickness was 213.5 ± 51.7 μm (126.1[FIGURE DASH]326.9 μm) at baseline and 129.6 ± 39.3 μm (65.9[FIGURE DASH]197.1 μm) at 12 months. In nonaffected contralateral eyes, the mean peripapillary choroidal thickness was 194.1 ± 39.8 μm (158.5[FIGURE DASH]238.3 μm) at baseline and 156.6 ± 56.2 μm (125.9[FIGURE DASH]213.9 μm) at 12 months. The mean peripapillary choroidal thickness decreased significantly over 12 months in both BRVO-affected and nonaffected eyes (P < 0.001, both eyes). Although the mean peripapillary choroidal thickness was not significantly different between groups at baseline (P = 0.472), it was significantly lower in BRVO-affected eyes than in nonaffected eyes at 12 months (P = 0.036).
CONCLUSION
Peripapillary choroidal thickness decreased significantly over 12 months in BRVO-affected eyes and nonaffected eyes in patients with unilateral BRVO.
目的
采用增强深度成像的光谱域光学相干断层扫描技术，评估视网膜分支静脉阻塞（BRVO）患者12个月期间视乳头周围脉络膜厚度的变化。
方法
本回顾性、干预性病例系列研究纳入20例未经治疗的单侧BRVO患者，随访至少12个月。测量其视乳头周围脉络膜厚度，为期12个月。
结果
在受BRVO影响的眼中，基线时视乳头周围脉络膜平均厚度为213.5±51.7μm（126.1[图横线]326.9μm），12个月时为129.6±39.3μm（65.9[图横线]197.1μm）。在未受影响的对侧眼中，基线时视乳头周围脉络膜平均厚度为194.1±39.8μm（158.5[图横线]238.3μm），12个月时为156.6±56.2μm（125.9[图横线]213.9μm）。在受BRVO影响的眼和未受影响的眼中，视乳头周围脉络膜平均厚度在12个月期间均显著下降（双眼P<0.001）。虽然两组在基线时视乳头周围脉络膜平均厚度无显著差异（P = 0.472），但在12个月时，受BRVO影响的眼的视乳头周围脉络膜平均厚度显著低于未受影响的眼（P = 0.036）。
结论
单侧BRVO患者中，受BRVO影响的眼和未受影响的眼的视乳头周围脉络膜厚度在12个月期间均显著下降。
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