癌症患儿的声带麻痹：对英国儿科重症监护病房收治情况的十年分析
Vocal Cord Palsy in Children With Cancer: A 10-Year Analysis of UK Pediatric Intensive Care Admissions.
作者信息
Capsomidis Anna, Hall Andrew, Daya Hamid, Round Jonathan, Lancaster Donna, Bate Jessica
机构信息
*Cancer Section, UCL Great Ormond Street Institute of Child Health †Department of Ears, Nose and Throat, Northwick Park Hospital Departments of ‡Ears, Nose and Throat §Paediatric Intensive Care, St. George's University Hospitals NHS Foundation Trust, London ∥The Royal Marsden NHS Foundation Trust, Sutton ¶Department of Paediatric Oncology and Haematology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
出版信息
J Pediatr Hematol Oncol. 2017 May;39(4):293-295. doi: 10.1097/MPH.0000000000000772.
Vocal cord palsy (VCP) is a rare but potentially life-threatening complication in children with cancer. This study reviews UK Intensive Care admissions for children with cancer and VCP using data obtained from the Pediatric Intensive Care Audit Network (PICANet) database. 26 children with cancer and VCP were admitted to intensive care from 2002 to 2012. The majority of admissions (23/26) required respiratory intervention (17 invasive ventilation, 8 noninvasive ventilation, and 5 tracheostomy). VCP should be considered early in children with cancer who present with signs of upper airway obstruction, especially in those receiving vinca-alkaloids as VCP is likely to be reversible.
声带麻痹（VCP）是癌症患儿中一种罕见但可能危及生命的并发症。本研究利用从儿科重症监护审计网络（PICANet）数据库获得的数据，回顾了英国癌症患儿合并VCP入住重症监护病房的情况。2002年至2012年期间，26例癌症合并VCP患儿入住重症监护病房。大多数患儿（23/26）需要呼吸干预（17例有创通气、8例无创通气和5例气管造口术）。对于出现上呼吸道梗阻症状的癌症患儿，尤其是接受长春花生物碱治疗的患儿，应尽早考虑VCP，因为VCP可能是可逆的。
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