Tian Jing, An Xinjiang, Fu Mingyu, Wang Qingwen
Department of Cardiology, Xuzhou Children's Hospital, Xuzhou, Jiangsu 221002, P.R. China.
Exp Ther Med. 2016 Dec;12(6):3557-3560. doi: 10.3892/etm.2016.3803. Epub 2016 Oct 12.
The clinical effects were compared and analyzed of traditional Chinese medicine (TCM) 'Ling Gui Long Mu soup' combined with the conventional Western medications in treating child typhoid complicated by myocarditis. From July, 2010 to May, 2014, 54 children suffering from typhoid complicated by myocarditis were enrolled in the present study. The patients were divided into the observation and control groups (n=27 cases per group) according to the random number table. Patients in the observation group were treated with basic Western medicine combined with TCM 'Ling Gui Long Mu soup' while patients in the control group were treated only with Western medicine. We analyzed the final curative effects in the two groups. The total effective rate in the observation group was significantly higher than that of the control group and the difference was statistically significant (P<0.05). The improvement rate of the syndrome in the TCM observation group was significantly higher than that in the control group and the difference was statistically significant (P<0.05). Although the C-reactive protein (CRP) and creatinine kinase-MB (CK-MB) levels in the two groups were decreased following the treatment, CRP and CK-MB levels in the observation group were further reduced, and the difference was statistically significant (P<0.05). In conclusion, for child typhoid complicated by myocarditis, TCM 'Ling Gui Long Mu soup' significantly improved the clinical efficiency of the treatment and improved the syndrome. Therefore, 'Ling Gui Long Mu soup' is useful in clinical practice.
比较分析了中药“苓桂龙牡汤”联合常规西药治疗小儿伤寒合并心肌炎的临床疗效。选取2010年7月至2014年5月期间收治的54例小儿伤寒合并心肌炎患者,按随机数字表法分为观察组和对照组,每组27例。观察组采用基础西药联合中药“苓桂龙牡汤”治疗,对照组仅采用西药治疗。分析两组最终疗效。结果显示,观察组总有效率显著高于对照组,差异有统计学意义(P<0.05);中医观察组证候改善率显著高于对照组,差异有统计学意义(P<0.05)。两组治疗后C反应蛋白(CRP)和肌酸激酶同工酶(CK-MB)水平均下降,但观察组CRP和CK-MB水平进一步降低,差异有统计学意义(P<0.05)。结论:对于小儿伤寒合并心肌炎,中药“苓桂龙牡汤”可显著提高临床治疗效果,改善证候,在临床实践中具有应用价值。