Hunter V, Tseng P
Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC 27710.
J Reprod Med. 1989 Sep;34(9):625-8.
Microcolposcopy (MC) can magnify cervical and endocervical surface cytology from 1:1 to 1:150. MC examination of the exocervix has been found to be equivalent to colposcopy. We compared MC to cone histology in evaluating the endocervix in women with inadequate colposcopy or positive endocervical curettage (ECC). Thirty-one patients were studied. All had standard colposcopic examinations that were deemed inadequate or resulted in positive ECC. MC was then performed and followed by cervical conization. Histologic specimens were obtained from serial sections of the surgical specimen. All 31 patients had adequate MC examinations. MC had a positive predictive value of 87% in evaluation of the endocervix as compared to cone histology specimens. Sensitivity and specificity were 99% and 70%, respectively. MC had a sensitivity of 92% in identifying the cervical segment with the worst histologic diagnosis. MC can evaluate the endocervix in patients with inadequate colposcopy or positive ECC. Biopsy of the worst histologic region in those patients can be guided by MC examination; thus, conization of the cervix can be avoided.
微型阴道镜检查（MC）可将宫颈和宫颈管内表面细胞学放大倍数从1:1提高到1:150。已发现对外宫颈进行MC检查等同于阴道镜检查。我们在评估阴道镜检查不充分或宫颈管刮术（ECC）阳性的女性的宫颈管时，将MC与锥形切除术组织学结果进行了比较。对31例患者进行了研究。所有患者均接受了标准阴道镜检查，这些检查被认为不充分或导致ECC阳性。然后进行MC检查，随后进行宫颈锥形切除术。从手术标本的连续切片中获取组织学标本。所有31例患者均进行了充分的MC检查。与锥形切除术组织学标本相比，MC在评估宫颈管时的阳性预测值为87%。敏感性和特异性分别为99%和70%。MC在识别组织学诊断最差的宫颈节段方面的敏感性为92%。MC可评估阴道镜检查不充分或ECC阳性患者的宫颈管。这些患者中组织学最差区域的活检可由MC检查引导；因此，可以避免宫颈锥形切除术。
