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波兰生物样本库网络BBMRI.pl的组织架构

Organization of BBMRI.pl: The Polish Biobanking Network.

作者信息

Witoń Małgorzata, Strapagiel Dominik, Gleńska-Olender Joanna, Chróścicka Anna, Ferdyn Katarzyna, Skokowski Jarosław, Kalinowski Leszek, Pawlikowski Jakub, Marciniak Błażej, Pasterk Markus, Matera-Witkiewicz Agnieszka, Kozera Łukasz

机构信息

1 Regional Science and Technology Center , Swietokrzyski Biobank, Checiny, Poland .

2 Biobank Lab, Department of Molecular Biophysics, University of Lodz , Lodz, Poland .

出版信息

Biopreserv Biobank. 2017 Jun;15(3):264-269. doi: 10.1089/bio.2016.0091. Epub 2017 Jan 19.

Abstract

In Poland storage of human biological samples takes place at most universities and scientific institutions conducting research projects in the field of biomedicine. The First International Biobanking Conference organized by the Ministry of Science and Higher Education in 2014 shed a light on the situation of Polish biobanking infrastructures. The country has around 40 large biorepositories, which store unique biological material such as whole brains, muscle fibers from patients with rare diseases, as well as thousands of samples from patients with lifestyle diseases. There are only two population-based biobanks working locally and several disease-oriented biobanks specializing mainly in oncological diseases. Consortium BBMRI.pl created plans for establishing a Polish Network of Biobanks, with national node which meets standards for biobanks and cooperation to guarantee development of biomedical sciences and international collaboration between Poland and other countries. The Polish network will enhance research activities, due to better visibility of samples and data that are stored in the national biobanking catalogue. However, it requires more than a comprehensive understanding of all benefits. The list of examples of benefits can be presented as follows: (i) a reduction of the duration and cost of clinical trials and subsequent time to market for anticancer drugs; (ii) more precise patient diagnosis and the associated impact on treatment and lower healthcare costs for providers, individuals, and the nation; (iii) improvements in research experiment time frames and data efficiencies; (iv) convergence to an industry standards for biospecimen quality; (v) optimization of capital infrastructure and IT technology.

摘要

在波兰,大多数开展生物医药领域研究项目的大学和科研机构都有人类生物样本的储存库。2014年由科学与高等教育部组织的第一届国际生物样本库会议揭示了波兰生物样本库基础设施的状况。该国约有40个大型生物样本库,储存着独特的生物材料,如全脑、罕见病患者的肌肉纤维,以及数千份生活方式疾病患者的样本。只有两个以人群为基础的生物样本库在当地开展工作,还有几个主要专注于肿瘤疾病的疾病导向型生物样本库。BBMRI.pl联盟制定了建立波兰生物样本库网络的计划,该网络有一个符合生物样本库标准的国家节点,并通过合作来保障生物医学科学的发展以及波兰与其他国家之间的国际合作。波兰网络将加强研究活动,因为存储在国家生物样本库目录中的样本和数据的可见性更高。然而,这需要对所有益处有全面的理解。益处的示例列表如下:(i)减少临床试验的持续时间和成本以及抗癌药物随后的上市时间;(ii)更精确的患者诊断以及对治疗的相关影响,同时降低提供者、个人和国家的医疗保健成本;(iii)改善研究实验的时间框架和数据效率;(iv)向生物样本质量的行业标准靠拢;(v)优化资本基础设施和信息技术。

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