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Utilizing a large-scale biobanking registry to assess patient priorities and preferences for cancer research and education.利用大型生物银行注册中心评估患者对癌症研究和教育的优先事项和偏好。
PLoS One. 2021 Feb 5;16(2):e0246686. doi: 10.1371/journal.pone.0246686. eCollection 2021.
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Prospective associations between vitamin D and depression in middle-aged adults: findings from the UK Biobank cohort.中年人群中维生素 D 与抑郁的前瞻性关联:来自英国生物库队列的研究结果。
Psychol Med. 2022 Jul;52(10):1866-1874. doi: 10.1017/S0033291720003657. Epub 2020 Oct 21.
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Factors Influencing Public Knowledge and Willingness to Participate in Biomedical Research in Jordan: A National Survey.影响约旦公众对生物医学研究的认知及参与意愿的因素:一项全国性调查。
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将样本捐赠给生物库的意愿与选定心理变量之间的关联。

Associations between the Willingness to Donate Samples to Biobanks and Selected Psychological Variables.

机构信息

Department of Humanities and Social Medicine, Medical University of Lublin, 20-093 Lublin, Poland.

Biobanking and Biomolecular Resources Research Infrastructure Poland, BBMRI.pl Consortium, 54-066 Wrocław, Poland.

出版信息

Int J Environ Res Public Health. 2022 Feb 23;19(5):2552. doi: 10.3390/ijerph19052552.

DOI:10.3390/ijerph19052552
PMID:35270246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8910049/
Abstract

Over the past few decades, there has been a dynamic development of biobanks collecting human biological material and data. Advances in biomedical research based on biobanks, however, are highly dependent on the successful enrolment and participation of human subjects. Therefore, it is crucial to recognise those factors affecting the willingness of individuals to participate in biomedical research. There are very few studies pointing to the role of trust, preferred values and specific psychological factors. The aim of our study was the analysis of the most significant relationships between selected moral and psychological variables (i.e., preferred values, types of trust and personality) and willingness to donate biological material to biobanks. The research was carried out on a Polish representative national sample of 1100 people over 18 years of age. Statistical methods with regression models were used during the analyses. The willingness to donate samples to a biobank was associated with different types of trust and specific values. Based on regression analysis, the most important factors related to the willingness to donate material to biobanks seemed to be (1) trust towards scientists and doctors and (2) selected preferred values such as knowledge, self-development and tradition. Other values or personality traits did not seem to be as important in this context. The obtained results can be useful in building the social responsibility of biobankers and scientists, issuing more appropriate opinions by research ethics committees and planning better communication strategies between participants and biobanks.

摘要

在过去的几十年中,生物银行收集人类生物材料和数据的发展非常迅速。然而,基于生物银行的生物医学研究的进展高度依赖于人类受试者的成功招募和参与。因此,认识到影响个人参与生物医学研究意愿的因素至关重要。很少有研究指出信任、偏好价值观和特定心理因素的作用。我们的研究旨在分析选定的道德和心理变量(即偏好价值观、信任类型和个性)与向生物银行捐赠生物材料的意愿之间的最显著关系。该研究在一个 1100 名 18 岁以上的波兰代表性全国样本中进行。在分析过程中使用了带有回归模型的统计方法。向生物银行捐赠样本的意愿与不同类型的信任和特定价值观有关。基于回归分析,与向生物银行捐赠材料的意愿最相关的重要因素似乎是(1)对科学家和医生的信任,以及(2)选定的偏好价值观,如知识、自我发展和传统。在这种情况下,其他价值观或个性特征似乎并不那么重要。研究结果可以用于建立生物银行家和科学家的社会责任,由研究伦理委员会发表更合适的意见,并为参与者和生物银行之间规划更好的沟通策略。