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Understanding AAA Pathobiology: A GWAS Leads the Way.

作者信息

Chasman Daniel I, Lawler Patrick R

机构信息

From the Division of Preventive Medicine (D.I.C., P.R.L.), Division of Genetics (D.I.C.), and Division of Cardiovascular Medicine (P.R.L.), Brigham and Women's Hospital, Boston, MA.

出版信息

Circ Res. 2017 Jan 20;120(2):259-261. doi: 10.1161/CIRCRESAHA.116.310395.

DOI:10.1161/CIRCRESAHA.116.310395
PMID:28104763
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5267556/
Abstract
摘要

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本文引用的文献

1
Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.腹主动脉瘤全基因组关联研究的荟萃分析确定了四个新的疾病特异性风险位点。
Circ Res. 2017 Jan 20;120(2):341-353. doi: 10.1161/CIRCRESAHA.116.308765. Epub 2016 Nov 29.
2
Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.颅内、腹部和胸段动脉瘤的共同遗传风险因素。
J Am Heart Assoc. 2016 Jul 14;5(7):e002603. doi: 10.1161/JAHA.115.002603.
3
Editor's Choice - High Heritability of Liability to Abdominal Aortic Aneurysms: A Population Based Twin Study.编辑推荐——腹主动脉瘤易感性的高遗传性：一项基于人群的双胞胎研究
Eur J Vasc Endovasc Surg. 2016 Jul;52(1):41-6. doi: 10.1016/j.ejvs.2016.03.012. Epub 2016 Apr 20.
4
Abdominal aortic aneurysm: novel mechanisms and therapies.腹主动脉瘤：新机制与治疗方法
Curr Opin Cardiol. 2015 Nov;30(6):566-73. doi: 10.1097/HCO.0000000000000216.
5
Factors associated with small abdominal aortic aneurysm expansion rate.与小腹部主动脉瘤扩张率相关的因素。
JAMA Surg. 2015 Jan;150(1):44-50. doi: 10.1001/jamasurg.2014.2025.
6
A variant in LDLR is associated with abdominal aortic aneurysm.低密度脂蛋白受体（LDLR）中的一个变体与腹主动脉瘤相关。
Circ Cardiovasc Genet. 2013 Oct;6(5):498-504. doi: 10.1161/CIRCGENETICS.113.000165. Epub 2013 Sep 17.
7
Impact of inherited genetic variants associated with lipid profile, hypertension, and coronary artery disease on the risk of intracranial and abdominal aortic aneurysms.与血脂水平、高血压和冠状动脉疾病相关的遗传变异对颅内和腹主动脉瘤风险的影响。
Circ Cardiovasc Genet. 2013 Jun;6(3):264-70. doi: 10.1161/CIRCGENETICS.113.000022. Epub 2013 May 9.
8
A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm.一个与 1p13.3 上的 sortilin-1（SORT1）相关的序列变异与腹主动脉瘤独立相关。
Hum Mol Genet. 2013 Jul 15;22(14):2941-7. doi: 10.1093/hmg/ddt141. Epub 2013 Mar 27.
9
Interleukin-6 receptor pathways in abdominal aortic aneurysm.腹主动脉瘤中的白细胞介素-6受体通路
Eur Heart J. 2013 Dec;34(48):3707-16. doi: 10.1093/eurheartj/ehs354. Epub 2012 Oct 30.
10
Matrix metalloproteinase-9 genotype as a potential genetic marker for abdominal aortic aneurysm.基质金属蛋白酶-9基因型作为腹主动脉瘤的潜在遗传标志物。
Circ Cardiovasc Genet. 2012 Oct 1;5(5):529-37. doi: 10.1161/CIRCGENETICS.112.963082. Epub 2012 Aug 31.