Takeuchi Hisashi, Tokuyama Naoto, Kuroda Isao, Aoyagi Teiichiro
Department of Urology, Tokyo Medical University Ibaraki Medical Center, Ibaraki 300-0395, Japan.
Mol Clin Oncol. 2016 Dec;5(6):842-844. doi: 10.3892/mco.2016.1047. Epub 2016 Oct 11.
A 69-year-old man was referred to our hospital with chief complaints of urinary incontinence, pollakiuria, thin stools and edema of the left lower extremity. Computed tomography and magnetic resonance imaging revealed bilateral hydronephrosis, thickening of the rectal and posterolateral bladder walls, and enlargement of the left obturator lymph nodes, suggesting metastasis. The carcinoembryonic antigen and carbohydrate antigen 19-9 levels were 5.6 ng/ml and 460.1 U/ml, respectively. A transurethral bladder biopsy revealed grade 2 urothelial carcinoma with glandular differentiation. A transrectal needle biopsy suggested cancer infiltration of the rectal wall and an annular rectal constriction caused by an infiltrating bladder cancer was diagnosed. Three courses of gemcitabine and cisplatin chemotherapy were administered and demonstrated good efficacy.
一名69岁男性因尿失禁、尿频、大便变细及左下肢水肿为主诉被转诊至我院。计算机断层扫描和磁共振成像显示双侧肾积水、直肠和膀胱后外侧壁增厚以及左闭孔淋巴结肿大，提示转移。癌胚抗原和糖类抗原19-9水平分别为5.6 ng/ml和460.1 U/ml。经尿道膀胱活检显示为2级伴腺性分化的尿路上皮癌。经直肠穿刺活检提示直肠壁癌浸润，诊断为浸润性膀胱癌导致的环状直肠狭窄。给予三疗程吉西他滨和顺铂化疗，显示出良好疗效。
