Mottillo Cristina, Friščić Tomislav
Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC H1P 1W1, Canada.
Molecules. 2017 Jan 17;22(1):144. doi: 10.3390/molecules22010144.
Controlling the formation of coordination bonds is pivotal to the development of a plethora of functional metal-organic materials, ranging from coordination polymers, metal-organic frameworks (MOFs) to metallodrugs. The interest in and commercialization of such materials has created a need for more efficient, environmentally-friendly routes for making coordination bonds. Solid-state coordination chemistry is a versatile greener alternative to conventional synthesis, offering quantitative yields, enhanced stoichiometric and topological selectivity, access to a wider range of precursors, as well as to molecules and materials not readily accessible in solution or solvothermally. With a focus on mechanochemical, thermochemical and "accelerated aging" approaches to coordination polymers, including pharmaceutically-relevant materials and microporous MOFs, this review highlights the recent advances in solid-state coordination chemistry and techniques for understanding the underlying reaction mechanisms.
控制配位键的形成对于众多功能金属有机材料的开发至关重要，这些材料包括配位聚合物、金属有机框架（MOF）以及金属药物。对此类材料的关注和商业化需求催生了对更高效、环境友好的配位键形成途径的需求。固态配位化学是传统合成方法的一种多功能且更环保的替代方法，它能提供定量产率、增强化学计量和拓扑选择性、可使用更广泛的前驱体，以及获得在溶液或溶剂热法中不易获得的分子和材料。本文聚焦于配位聚合物的机械化学、热化学和“加速老化”方法，包括与药物相关的材料和微孔MOF，重点介绍了固态配位化学的最新进展以及理解潜在反应机制的技术。
