Blanchard Brittany E, Stevens Angela K, Littlefield Andrew K, Talley Amelia E, Brown Jennifer L
Department of Psychological Sciences, MS 2051 Psychological Sciences Building, Texas Tech University, Lubbock, TX 79409-2051, USA.
Department of Psychological Sciences, MS 2051 Psychological Sciences Building, Texas Tech University, Lubbock, TX 79409-2051, USA.
Addict Behav. 2017 Jun;69:8-13. doi: 10.1016/j.addbeh.2017.01.003. Epub 2017 Jan 6.
The association between impulsive dispositions and the use of the central nervous system (CNS) depressant alcohol has been examined extensively; however, the links between other depressant use (sedatives, tranquilizers, and pain relievers) and impulsivity have been less studied, and findings have been equivocal. This may be due, in part, to varying operationalizations of "impulsivity," as well as issues related to the lumping versus splitting of various depressant substances when assessing use. The effect of gender on the impulsivity-depressant use relation has also yielded mixed results and remains understudied. The current study sought to determine whether lumping versus splitting of depressant substances and distinct impulsivity-related dispositions, as well as participant gender, impact the depressant-impulsivity relation.
Participants were 778 undergraduate students (72% female, 80% White, 23% Hispanic), who completed a battery of self-report assessments online, including the UPPS-P.
Hierarchical linear models indicated that specific impulsive dispositions differentiated between users and non-users of specific depressant substances, and these relations varied by gender. For example, sensation seeking significantly differentiated between users and non-users of pain relievers for females only, whereas sensation seeking differentiated between users and non-users of tranquilizers among males but not females.
In addition to informing substance use research practices by providing evidence that lumping of depressant substances leads to loss of vital information, as well as demonstrating nuanced gender differences, findings can also inform screening and personality-targeted treatment practices.
冲动性倾向与中枢神经系统（CNS）抑制剂酒精的使用之间的关联已得到广泛研究；然而，其他抑制剂（镇静剂、 tranquilizers和止痛药）的使用与冲动性之间的联系研究较少，且结果不一。这可能部分是由于“冲动性”的不同操作定义，以及在评估使用情况时与各种抑制剂物质的合并与细分相关的问题。性别对冲动性与抑制剂使用关系的影响也产生了混合结果，仍有待进一步研究。本研究旨在确定抑制剂物质的合并与细分、与冲动性相关的不同倾向以及参与者性别是否会影响抑制剂与冲动性的关系。
参与者为778名本科生（72%为女性，80%为白人，23%为西班牙裔），他们在线完成了一系列自我报告评估，包括UPPS-P。
分层线性模型表明，特定的冲动性倾向在特定抑制剂物质的使用者和非使用者之间存在差异，且这些关系因性别而异。例如，寻求刺激仅在女性中显著区分了止痛药使用者和非使用者，而寻求刺激在男性中区分了镇静剂使用者和非使用者，但在女性中没有。
除了通过提供证据表明抑制剂物质的合并会导致重要信息的丢失，以及展示细微的性别差异来为物质使用研究实践提供信息外，研究结果还可以为筛查和针对个性的治疗实践提供信息。
