Matsutani M, Nakamura O, Nagashima T, Ueki K, Nakamura M
Dept. of Neurosurgery, Tokyo Metropolitan Komagome Hospital.
Gan No Rinsho. 1989 Sep;35(11):1227-32.
One hundred one patients with glioblastoma were studied to evaluate the effect of the extent of surgical resection on the length and quality of life. Extensive removal of tumor was performed for 45 patients, while the remaining 56 patients underwent partial removal or biopsy of tumor. The median time to tumor progression and the median survival in the former patients were 18.0 months and 23.0 months, respectively, and, in the latter patients, 6.0 months and 10.0 months, respectively. More than 80% of Karnofsky rating was observed in 69% of the former patients. Extensive removal of glioblastoma would be associated with longer and better survival when compared to partial removal.
