Bernardi Daniela, Houssami Nehmat
U.O. Senologia Clinica e Screening Mammografico, Department of Diagnostics, Ospedale di Trento, Azienda Provinciale Servizi Sanitari, Trento, Italy.
Sydney School of Public Health, Sydney Medical School, University of Sydney, Sydney, Australia.
Breast. 2017 Apr;32:98-101. doi: 10.1016/j.breast.2017.01.005. Epub 2017 Jan 18.
The prospective 'screening with tomosynthesis or standard mammography-2 (STORM-2)' trial compared mammography screen-reading strategies and showed that each of integrated 2D/3D-mammography or 2Dsynthetic/3D-mammography detected significantly more breast cancers than 2D-mammography alone. This short report describes 13 (from 90) cancers detected in only one of two parallel double-reading arms implemented in STORM-2. Amongst this subset of cases, the majority was invasive cancer ≤16 mm, mostly depicted as irregular masses or distortions. Furthermore, most were detected at 3D-mammography only and predominantly by one reader from double-reading pairs, highlighting that 3D-mammography may enable detection of cancers that are challenging to perceive at routine screening.
前瞻性的“断层合成或标准乳腺X线摄影筛查-2（STORM-2）”试验比较了乳腺X线摄影的阅片策略，结果显示，与单独使用二维乳腺X线摄影相比，集成二维/三维乳腺X线摄影或二维合成/三维乳腺X线摄影检测出的乳腺癌显著更多。本简短报告描述了在STORM-2实施的两个平行双读组之一中仅检测到的13例（共90例）癌症。在这一亚组病例中，大多数为浸润性癌，最大径≤16mm，多表现为不规则肿块或结构扭曲。此外，大多数病例仅在三维乳腺X线摄影时被检测到，且主要由双读组中的一位阅片者发现，这突出表明三维乳腺X线摄影可能有助于检测出在常规筛查中难以发现的癌症。
