艾达司珠单抗用于达比加群的逆转 - Suppr

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超能文献

Idarucizumab for the Reversal of Dabigatran.

作者信息

Gottlieb Michael, Khishfe Basem

机构信息

Department of Emergency Medicine, Rush University Medical Center, Chicago, IL.

Department of Emergency Medicine, Mount Sinai Hospital, Chicago, IL.

出版信息

Ann Emerg Med. 2017 May;69(5):554-558. doi: 10.1016/j.annemergmed.2016.11.025. Epub 2017 Jan 19.

DOI:10.1016/j.annemergmed.2016.11.025

PMID:28110992

Abstract

摘要

相似文献

Idarucizumab for the Reversal of Dabigatran.艾达司珠单抗用于达比加群的逆转

Ann Emerg Med. 2017 May;69(5):554-558. doi: 10.1016/j.annemergmed.2016.11.025. Epub 2017 Jan 19.

[Goal-directed administration of antidote for reversal of dabigatran anticoagulation].[达比加群抗凝逆转的解毒剂目标导向给药]

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Safety, tolerability, and efficacy of idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: a randomised, placebo-controlled, double-blind phase 1 trial.达比加群酯逆转剂依达鲁珠单抗在健康男性志愿者中的安全性、耐受性和疗效：一项随机、安慰剂对照、双盲的 1 期临床试验。

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Idarucizumab, a specific reversal agent for dabigatran: mode of action, pharmacokinetics and pharmacodynamics, and safety and efficacy in phase 1 subjects.依达赛珠单抗，一种达比加群的特异性逆转剂：作用机制、药代动力学和药效学，以及在1期受试者中的安全性和有效性。

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A randomised study in healthy volunteers to investigate the safety, tolerability and pharmacokinetics of idarucizumab, a specific antidote to dabigatran.一项在健康志愿者中开展的随机研究，旨在调查达比加群的特异性解毒剂艾达司珠单抗的安全性、耐受性和药代动力学。

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Spotlight on idarucizumab and its potential for the reversal of anticoagulant effects of dabigatran.关注艾达司珠单抗及其逆转达比加群抗凝作用的潜力。

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Dose requirements for idarucizumab reversal of dabigatran in a lethal porcine trauma model with continuous bleeding.达比加群酯拮抗剂依达鲁珠单抗逆转持续出血致死性猪创伤模型的剂量需求。

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