Santhini P V, Nimisha G, John Jubi, Suresh E, Varma R Luxmi, Radhakrishnan K V
Academy of Scientific and Innovative Research (AcSIR), New Delhi 110001, India and Organic Chemistry Section, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695019, India.
Central Salt and Marine Chemicals Research Institute, Bhavnagar 364 002, India.
Chem Commun (Camb). 2017 Feb 2;53(11):1848-1851. doi: 10.1039/c6cc08753a.
An efficient stereoselective route for the synthesis of cyclopentene fused 2-pyrrolines has been established via a Pd-catalyzed C-H activation/oxidative coupling of aryl enamides with diazabicyclic olefins. The proposed two-stage mechanism was successfully proven by isolating the intermediate trans-disubstituted cyclopentene.
通过钯催化的芳基烯酰胺与二氮杂双环烯烃的C-H活化/氧化偶联反应，建立了一种高效立体选择性合成环戊烯稠合2-吡咯啉的方法。通过分离中间体反式二取代环戊烯，成功证明了所提出的两步反应机理。
