Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka, 565-0871, Japan.
Angew Chem Int Ed Engl. 2017 Feb 20;56(9):2435-2439. doi: 10.1002/anie.201610047. Epub 2017 Jan 23.
In the presence of Ni /PCy , styrene was found to participate in oxidative cyclization with tetrafluoroethylene, thus leading to the corresponding nickelacycle with a unique η -π-benzyl structure. In addition, the flexibility of the coordination mode in the η -benzyl moiety allowed the partially fluorinated nickelacycle to undergo unprecedented amine-induced α-fluorine elimination, thus leading to the construction of a fluorinated cyclobutyl skeleton.
在 Ni/PCy 的存在下，苯乙烯被发现与四氟乙烯发生氧化环化反应，从而生成具有独特 η-π-苄基结构的镍杂环。此外，η-苄基部分配位模式的灵活性允许部分氟化的镍杂环发生前所未有的胺诱导的α-氟消除反应，从而构建了氟化的环丁基骨架。
