Alberca de Las Parras Fernando, Egea Valenzuela Juan, Carballo Álvarez Fernando
Digestivo/endocopias, Hospital Clínico Universitario Virgen de la Arrixaca, España.
Unidad de Gestión Clínica digestivo, Hospital Clínico Universitario Virgen de la Arrixaca.
Rev Esp Enferm Dig. 2017 Mar;109(3):202-210. doi: 10.17235/reed.2017.4358/2016.
To analyze the risk factors for hemorrhage during endoscopic retrograde cholangiopancreatography and the impact of antithrombotic drugs.
Data sources: papers indexed in PubMed have been reviewed, as well as those found during the analysis of the bibliography of meta-analysis and reviews.
the references have been firstly evaluated by review of the abstract. After selecting the most significant articles (mainly randomized trials and well-designed case series) these have been deeply analyzed. Evaluation of the studies and synthesis: criteria by the Oxford Centre for Evidence-Based Medicine have been used for the analysis of the references and elaboration of evidence levels.
Seven hundred and sixty-five references were found, 753 in PubMed and the Cochrane Library. Twelve studies were selected during the analysis of other published articles (systematic reviews, meta-analysis and clinical practice guidelines). After analyzing the title or the abstract, 655 studies were excluded. Finally, 83 high quality trials or descriptive studies have been included in the analysis.
Seven conclusions regarding the risk factors for bleeding and the impact of antithrombotic drugs have been defined.
分析内镜逆行胰胆管造影术期间出血的危险因素以及抗血栓药物的影响。
数据来源：对PubMed索引的论文以及在分析荟萃分析和综述的参考文献期间发现的论文进行了审查。
参考文献首先通过摘要审查进行评估。在选择最重要的文章（主要是随机试验和设计良好的病例系列）后，对这些文章进行了深入分析。研究评估与综合：采用牛津循证医学中心的标准对参考文献进行分析并确定证据水平。
共找到765篇参考文献，其中753篇来自PubMed和Cochrane图书馆。在分析其他已发表文章（系统评价、荟萃分析和临床实践指南）期间选择了12项研究。在分析标题或摘要后，排除了655项研究。最终，83项高质量试验或描述性研究被纳入分析。
确定了关于出血危险因素和抗血栓药物影响的七条结论。
