Department of Dermatology, Leiden University Medical Centre, Leiden, the Netherlands.
Bahrain Branch of Cochrane, Awali, Bahrain.
JAMA Dermatol. 2017 Mar 1;153(3):329-330. doi: 10.1001/jamadermatol.2016.5790.
Which interventions are effective and safe for treating female pattern hair loss (FPHL)?
There was low- to moderate-quality evidence that topical minoxidil (2% and 5%) was associated with improvements in FPHL. There was low-quality evidence that finasteride was no more effective than placebo. There were inconsistent results from studies that laser devices were effective, but total hair count increased compared with baseline (moderate- to low-quality evidence). Most treatments were not associated with higher adverse event rates than placebo.
哪些干预措施对于治疗女性型脱发（FPHL）既有效又安全？
低到中等质量的证据表明，外用米诺地尔（2%和 5%）与 FPHL 的改善相关。低质量的证据表明，非那雄胺并不比安慰剂更有效。激光设备有效的研究结果不一致，但与基线相比，总发量增加（中等至低质量证据）。与安慰剂相比，大多数治疗方法并未导致更高的不良事件发生率。
