Elnady Rana E, Abdon Manar S, Shaheen Hagar R, Eladawy Reem M, Azar Yasmena O, Al Raish Seham M
Department of Pharmaceutics, Faculty of Pharmacy, Sinai University-Arish Branch, Arish 45511, Egypt.
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Sinai University-Arish Branch, Arish 45511, Egypt.
Pharmaceutics. 2025 Apr 29;17(5):584. doi: 10.3390/pharmaceutics17050584.
Alopecia is a concerning dermatological issue and is also known as alopecia. This disease can affect men and women, influencing their confidence and appearance. It targets the scalp or any area of the entire body. Alopecia has become widespread worldwide over the years and has many types and different causes: hereditary, hormonal, immunological, therapeutic, or psychological. This review will present a comprehensive study of the physiological structure of hair and the different growth and shedding phases. It discusses using nano-drug delivery systems that contain natural substances of plant origin, which are effective, less harmful compared to current treatments, and help avoid adverse effects. This review also covers the latest trends in treating alopecia, including drug delivery systems, the materials and methods used to prepare these systems, three-dimensional (3D) bioprinting strategies, and plant extracts that may be utilized for treatment in the coming years.
脱发是一个令人担忧的皮肤病问题，也被称为秃发症。这种疾病会影响男性和女性，影响他们的自信心和外貌。它针对头皮或全身的任何部位。多年来，脱发在全球范围内广泛存在，有多种类型和不同病因：遗传、激素、免疫、治疗或心理因素。本综述将对头发的生理结构以及不同的生长和脱落阶段进行全面研究。它讨论了使用含有植物源天然物质的纳米药物递送系统，这些系统有效，与当前治疗方法相比危害较小，并有助于避免不良反应。本综述还涵盖了脱发治疗的最新趋势，包括药物递送系统、用于制备这些系统的材料和方法、三维（3D）生物打印策略以及未来几年可能用于治疗的植物提取物。
