Vincerževskiene Ieva, Jasilionis Domantas, Austys Donatas, Stukas Rimantas, Kaceniene Auguste, Smailyte Giedre
Laboratory of Cancer Epidemiology, National Cancer Institute, Vilnius, Lithuania.
Laboratory for Demographic Data, Max Planck Institute for Demographic Research, Rostock, Germany.
Eur J Public Health. 2017 Jun 1;27(3):421-424. doi: 10.1093/eurpub/ckw261.
: We examined inequalities in cervical cancer survival in Lithuania by education and place of residence. : The study is based on the linked dataset that includes all records of the 2001 population Census, all records from Lithuanian Cancer Registry (cancer incidence) and all death and emigration records from Statistics Lithuania for the period between 6 April 2001 and 31 December 2009. The study group includes cervical cancers registered in the Cancer Registry from 1 January 2002 to 31 December 2006. Analysis was restricted to women who were 25-64 years old at the Census date (in total 1 866 cases). : During the study period there were 671 deaths corresponding to an overall 5-year survival proportion 64.13% (95% CI 61.86-66.31). Place of residence and education of cervical cancer patients had strong impact on survival; 5-year survival was higher in women living in urban areas than in rural (68.61 and 55.93%) and survival decreased with decreasing education: from 79.77% in highest education group to 64.85 and 50.48% in groups with secondary and lower than secondary education. The effect of place of residence declined when stage of disease was included in the model and became not significant in final model with education adjustment. The effect of education declined after inclusion of stage and other variables, however, remained significant. : We found that women with higher education experienced higher survival following a cervical cancer diagnosis, and stage of disease at the time of diagnosis explains only the part of observed differences.
我们通过教育程度和居住地调查了立陶宛宫颈癌患者生存情况的不平等现象。
该研究基于一个关联数据集,其中包括2001年人口普查的所有记录、立陶宛癌症登记处(癌症发病率)的所有记录以及立陶宛统计局2001年4月6日至2009年12月31日期间的所有死亡和移民记录。研究组包括2002年1月1日至2006年12月31日在癌症登记处登记的宫颈癌患者。分析仅限于在普查日期时年龄在25至64岁之间的女性(共1866例)。
在研究期间,有671例死亡,总体5年生存率为64.13%(95%可信区间61.86 - 66.31)。宫颈癌患者的居住地和教育程度对生存有很大影响;城市地区女性的5年生存率高于农村地区(分别为68.61%和55.93%),且生存率随教育程度降低而下降:最高教育组为79.77%,中等教育组为64.85%,低于中等教育组为50.48%。当疾病分期纳入模型时,居住地的影响减弱,在最终经教育程度调整的模型中变得不显著。教育程度的影响在纳入分期和其他变量后减弱,但仍具有显著性。
我们发现,宫颈癌诊断后,受过高等教育的女性生存率更高,且诊断时的疾病分期仅解释了部分观察到的差异。