Terr L I, Sfogliano G A, Riley S L
House Ear Institute, Los Angeles, CA 90057.
Laryngoscope. 1989 Nov;99(11):1171-4. doi: 10.1288/00005537-198911000-00013.
Degeneration of the cochlear nerve before and after placement of the cochlear implant might influence the efficacy of the device. We examined histological characteristics, including the caliber of the cochlear nerve fibers of the central segment proximal to the porus acusticus, in three profoundly deaf patients. Two of them used a cochlear implant for many years longer in one ear than in the other, and one used an implant in one ear only. No qualitative or quantitative differences between the two sides were found. However, in all three cases we found that the cochlear nerves on both sides were substantially degenerated. These results indicated no noticeable effects of stimulation by the cochlear implant on the central portion of the cochlear nerve.
人工耳蜗植入前后蜗神经的退变可能会影响该装置的疗效。我们检查了3名极重度耳聋患者的组织学特征，包括靠近外耳道孔的中央段蜗神经纤维的直径。其中2名患者在一只耳朵使用人工耳蜗的时间比另一只耳朵长很多年，另1名患者仅在一只耳朵使用了人工耳蜗。未发现两侧在定性或定量方面存在差异。然而，在所有3例病例中，我们发现两侧的蜗神经均有明显退变。这些结果表明人工耳蜗刺激对蜗神经中枢部分没有明显影响。
