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成功治疗与恙虫病相关的急性横贯性脊髓炎及系列影像表现

Successfully Managed Acute Transverse Myelitis Related to Scrub Typhus and Serial Image Findings.

作者信息

Yun Jae Sung, Song Ji Soo, Choi Eun Jung, Hwang Jeong-Hwan, Lee Chang-Seop, Park Eun Hae

机构信息

Seoul Regional Military Manpower Administration, Seoul, Korea.

Department of Radiology, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.

出版信息

Am J Trop Med Hyg. 2017 Mar;96(3):557-560. doi: 10.4269/ajtmh.16-0524. Epub 2017 Apr 6.

DOI:10.4269/ajtmh.16-0524
PMID:28115665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5361527/
Abstract

Central nervous system involvement manifesting as meningitis or meningoencephalitis is a known complication of scrub typhus, but very few spinal cord lesions such as acute transverse myelitis (ATM) have been reported in association with this disease. Scrub typhus patients with a spinal lesion present with neurologic symptoms including dysuria, motor, and sensory weakness. Herein, we describe a rare case of ATM associated with scrub typhus. Clinical characteristics, cerebrospinal fluid cytology, serum antibody titer, and serial magnetic resonance imaging scans resulted in a diagnosis of ATM associated with scrub typhus.

摘要

中枢神经系统受累表现为脑膜炎或脑膜脑炎是恙虫病已知的并发症,但与该疾病相关的脊髓病变如急性横贯性脊髓炎(ATM)报道极少。有脊髓病变的恙虫病患者会出现包括排尿困难、运动和感觉无力等神经症状。在此,我们描述一例与恙虫病相关的罕见急性横贯性脊髓炎病例。通过临床特征、脑脊液细胞学检查、血清抗体滴度以及系列磁共振成像扫描确诊为与恙虫病相关的急性横贯性脊髓炎。

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Acute transverse myelitis following scrub typhus: A case report and review of the literature.恙虫病后急性横贯性脊髓炎:病例报告及文献复习。
J Spinal Cord Med. 2020 Jul;43(4):548-551. doi: 10.1080/10790268.2017.1420538. Epub 2018 Jan 19.

本文引用的文献

1
Scrub typhus with longitudinally extensive transverse myelitis.恙虫病合并纵向广泛横贯性脊髓炎
J Vector Borne Dis. 2016 Mar;53(1):84-6.
2
Guillain-Barré syndrome.格林-巴利综合征。
Lancet. 2016 Aug 13;388(10045):717-27. doi: 10.1016/S0140-6736(16)00339-1. Epub 2016 Mar 2.
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Scrub typhus meningoencephalitis, a diagnostic challenge for clinicians: A hospital based study from North-East India.恙虫病性脑膜脑炎:临床医生面临的诊断挑战——一项来自印度东北部的医院研究
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Scrub typhus meningitis or meningoencephalitis.恙虫病脑膜炎或脑膜脑炎。
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Differential diagnosis of scrub typhus meningitis from bacterial meningitis using clinical and laboratory features.恙虫病性脑膜炎与细菌性脑膜炎的临床和实验室特征鉴别诊断。
Neurol India. 2013 Jan-Feb;61(1):17-20. doi: 10.4103/0028-3886.107919.
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Pathologic study of thirty-one cases of scrub typhus fever with especial reference to the cardiovascular system.31例恙虫病的病理学研究,特别关注心血管系统。
Am Heart J. 1946 Mar;31:314-28. doi: 10.1016/0002-8703(46)90313-4.
8
Clinical and laboratory findings associated with severe scrub typhus.伴有严重恙虫病的临床和实验室发现。
BMC Infect Dis. 2010 Apr 30;10:108. doi: 10.1186/1471-2334-10-108.
9
Risk factors leading to fatal outcome in scrub typhus patients.恙虫病患者出现致命结局的危险因素。
Am J Trop Med Hyg. 2009 Sep;81(3):484-8.
10
Polyneuropathy and cerebral infarction complicating scrub typhus.恙虫病合并多发性神经病和脑梗死。
J Clin Neurol. 2008 Mar;4(1):36-9. doi: 10.3988/jcn.2008.4.1.36. Epub 2008 Mar 20.