Department of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea.
Department of Biostatistics, Korea University College of Medicine, Seoul, Republic of Korea.
Can J Gastroenterol Hepatol. 2016;2016:2198163. doi: 10.1155/2016/2198163. Epub 2016 Dec 26.
. Cardiac varices (CVs) in patients with type 1 gastroesophageal varices (GOV1s) usually disappear with treatment for esophageal varices (EVs) by endoscopic injection sclerotherapy (EIS). However, whether this applies to patients treated with endoscopic band ligation (EBL) for EVs remains unclear. We evaluated the effect of EVs eradication by EBL on CVs. . We included cirrhotic patients whose EVs had been eradicated using EBL and excluded those who had been treated using EIS, those who had received endoscopic therapy for CVs, and those who were combined with hepatocellular carcinoma. . A total of 123 patients were enrolled. The age was 59.7 ± 11.7 years, and 96 patients (78.0%) were men. Thirty-eight patients (30.9%) had EVs only, while 85 (69.1%) had GOV1s. After EVs eradication, the CVs disappeared in 55 patients (64.7%). EVs recurred in 40 patients, with recurrence rates at 1, 2, and 3 years of 16.0%, 29.6%, and 35.6%, respectively, the recurrence being more frequent in patients who had undergone EBL for secondary prophylaxis and in those with persisting CVs after EVs eradication ( = 0.003). . CVs frequently disappeared when EVs were eradicated using EBL in patients with GOV1s. Persistence of CVs after EVs eradication by EBL was associated with EVs recurrence.
. 1 型胃食管静脉曲张(GOV1)患者的心脏静脉曲张(CVs)通常在接受内镜下注射硬化疗法(EIS)治疗食管静脉曲张(EVs)后消失。然而,对于接受内镜套扎治疗(EBL)EVs 的患者是否如此尚不清楚。我们评估了 EBL 根除 EVs 对 CVs 的影响。. 我们纳入了通过 EBL 根除 EVs 的肝硬化患者,并排除了接受 EIS 治疗、接受 CVs 内镜治疗以及合并肝细胞癌的患者。. 共纳入 123 例患者。年龄为 59.7 ± 11.7 岁,96 例(78.0%)为男性。38 例(30.9%)仅有 EVs,85 例(69.1%)为 GOV1。根除 EVs 后,55 例(64.7%)CVs 消失。40 例患者出现 EVs 复发,复发率在 1、2、3 年分别为 16.0%、29.6%和 35.6%,在接受 EBL 二级预防和 EVs 根除后持续存在 CVs 的患者中复发更为频繁( = 0.003)。. 在 GOV1 患者中,EBL 根除 EVs 时 CVs 常消失。EBL 根除 EVs 后 CVs 持续存在与 EVs 复发有关。