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掺铽的氟化镧纳米晶体可用于相关的共聚焦离子束切片生物样本的阴极发光电子显微镜成像,具有纳米级分辨率。

Tb-doped LaF nanocrystals for correlative cathodoluminescence electron microscopy imaging with nanometric resolution in focused ion beam-sectioned biological samples.

机构信息

Particles-Biology Interactions, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland.

Reliability Science and Technology, Department Materials Meet Life, Swiss Federal Laboratories for Materials Science and Technology (Empa), Uberlandstrasse 129, 8600 Dubendorf, Switzerland.

出版信息

Nanoscale. 2017 Mar 30;9(13):4383-4387. doi: 10.1039/c6nr09187c.

Abstract

Here, we report the use of rare earth element-doped nanocrystals as probes for correlative cathodoluminescence electron microscopy (CCLEM) bioimaging. This first experimental demonstration shows potential for the simultaneous acquisition of luminescence and electron microscopy images with nanometric resolution in focused ion beam cut biological samples.

摘要

在这里,我们报告了使用稀土元素掺杂纳米晶体作为相关的阴极发光电子显微镜(CCLEM)生物成像探针。这一首次实验证明了在聚焦离子束切割生物样本中,以纳米级分辨率同时获取发光和电子显微镜图像的可能性。

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