van der Meer P F, Devine D V
Department of Product and Process Development, Sanquin Blood Bank, Amsterdam, The Netherlands.
Canadian Blood Services, Vancouver, BC, Canada.
Vox Sang. 2017 Feb;112(2):183-184. doi: 10.1111/vox.12479. Epub 2017 Jan 24.
The use of di-ethylhexyl-phthalate (DEHP) in blood bags is under discussion due to toxicity concerns and possible restrictions. A questionnaire among 15 blood centres in nine countries showed that none so far have fully switched to non-DEHP blood bags. If centres had to change, sites with a 42-day outdate would choose for a shorter outdating period, while others would allow a higher haemolysis rate (but within current specifications). To improve red cell quality, about half of the centres are willing to move to an alternative red cell storage solution, while the other half would not change for various reasons.
由于对毒性的担忧以及可能的限制，血液袋中邻苯二甲酸二（2-乙基己基）酯（DEHP）的使用正在讨论中。一项针对9个国家15个血液中心的问卷调查显示，目前尚无一家完全改用不含DEHP的血液袋。如果各中心必须做出改变，对于有效期为42天的血液，这些中心会选择更短的有效期，而其他中心则会允许更高的溶血率（但需在当前规格范围内）。为提高红细胞质量，约一半的中心愿意改用替代的红细胞保存液，而另一半则因各种原因不会做出改变。
