原发性皮肤弥漫性大 B 细胞淋巴瘤表现为慢性不愈合性溃疡。
Primary cutaneous diffuse large B-cell lymphoma presenting as chronic non-healing ulcer.
机构信息
Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, FL, USA.
Department of Dermatology, University of Pisa, Pisa, Italy.
出版信息
Int Wound J. 2017 Oct;14(5):830-832. doi: 10.1111/iwj.12716. Epub 2017 Jan 24.
Abstract
Primary cutaneous diffuse large B-cell lymphoma is an uncommon and aggressive lymphoproliferative disorder with a rapid growth rate and dismal prognosis. We present the case of a 91-year-old female with an unusual manifestation of primary cutaneous diffuse large B-cell lymphoma, mimicking other more prevalent diseases like chronic non-healing venous ulceration. Dermatopathologic evaluation rendered the correct diagnosis. A discussion of this rare presentation is important for clinician consideration to prevent misdiagnosis and prolongation of proper management in patients with chronic non-healing leg ulcers.
摘要
原发性皮肤弥漫性大 B 细胞淋巴瘤是一种罕见且侵袭性的淋巴增生性疾病，具有快速生长速度和不良预后。我们报告了一例 91 岁女性的原发性皮肤弥漫性大 B 细胞淋巴瘤的不典型表现，类似于其他更为常见的疾病，如慢性难愈性静脉溃疡。皮肤病理评估做出了正确的诊断。讨论这种罕见表现对于临床医生的考虑很重要，以防止误诊和延长慢性难愈性腿部溃疡患者的适当治疗。
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本文引用的文献
1
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J Am Acad Dermatol. 2015 Jun;72(6):1016-20. doi: 10.1016/j.jaad.2015.02.1134. Epub 2015 Mar 29.
2
Primary cutaneous diffuse large B-cell lymphoma, leg type and secondary cutaneous involvement by testicular B-cell lymphoma share identical clinicopathological and immunophenotypical features.原发性皮肤弥漫性大 B 细胞淋巴瘤，腿型和睾丸 B 细胞淋巴瘤继发皮肤累及具有相同的临床病理和免疫表型特征。
J Am Acad Dermatol. 2012 Apr;66(4):650-4. doi: 10.1016/j.jaad.2011.03.031. Epub 2011 Aug 3.
3
The 2008 WHO classification of lymphomas: implications for clinical practice and translational research.2008 年世界卫生组织淋巴瘤分类：对临床实践和转化研究的影响。
Hematology Am Soc Hematol Educ Program. 2009:523-31. doi: 10.1182/asheducation-2009.1.523.
4
European Organization for Research and Treatment of Cancer and International Society for Cutaneous Lymphoma consensus recommendations for the management of cutaneous B-cell lymphomas.欧洲癌症研究与治疗组织及国际皮肤淋巴瘤协会关于皮肤B细胞淋巴瘤管理的共识建议
Blood. 2008 Sep 1;112(5):1600-9. doi: 10.1182/blood-2008-04-152850. Epub 2008 Jun 20.
5
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Acta Derm Venereol. 2007;87(2):169-70. doi: 10.2340/00015555-0202.
6
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Blood. 2005 May 15;105(10):3768-85. doi: 10.1182/blood-2004-09-3502. Epub 2005 Feb 3.
7
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