Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, FL, USA.
Department of Dermatology, University of Pisa, Pisa, Italy.
Int Wound J. 2017 Oct;14(5):830-832. doi: 10.1111/iwj.12716. Epub 2017 Jan 24.
Primary cutaneous diffuse large B-cell lymphoma is an uncommon and aggressive lymphoproliferative disorder with a rapid growth rate and dismal prognosis. We present the case of a 91-year-old female with an unusual manifestation of primary cutaneous diffuse large B-cell lymphoma, mimicking other more prevalent diseases like chronic non-healing venous ulceration. Dermatopathologic evaluation rendered the correct diagnosis. A discussion of this rare presentation is important for clinician consideration to prevent misdiagnosis and prolongation of proper management in patients with chronic non-healing leg ulcers.
原发性皮肤弥漫性大 B 细胞淋巴瘤是一种罕见且侵袭性的淋巴增生性疾病,具有快速生长速度和不良预后。我们报告了一例 91 岁女性的原发性皮肤弥漫性大 B 细胞淋巴瘤的不典型表现,类似于其他更为常见的疾病,如慢性难愈性静脉溃疡。皮肤病理评估做出了正确的诊断。讨论这种罕见表现对于临床医生的考虑很重要,以防止误诊和延长慢性难愈性腿部溃疡患者的适当治疗。