Vijaya Basavaraj, Narahari Saravu RamaBhatta, Shruthi Mysore Krishna, Aggithaaya Guruprasad
Department of Pathology, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, India.
Institute of Applied Dermatology, Kasargod, Kerala, India.
Indian J Pathol Microbiol. 2019 Jul-Sep;62(3):470-472. doi: 10.4103/IJPM.IJPM_581_18.
A rare complication of chronic lymphedema is development of cutaneous malignant tumors particularly cutaneous lymphomas. We report a case of primary cutaneous diffuse large B-cell lymphoma, leg type, associated with chronic lymphedema of the lower limbs. A literature review identified 12 additional cases of primary cutaneous lymphomas associated with chronic lymphedema. Chronic lymphatic stasis may cause a local dysfunction of the immune system that predisposes to the induction of neoplasia, cutaneous lymphomas in particular.
慢性淋巴水肿的一种罕见并发症是皮肤恶性肿瘤尤其是皮肤淋巴瘤的发生。我们报告一例原发性皮肤弥漫性大B细胞淋巴瘤，腿部型，与下肢慢性淋巴水肿相关。文献回顾发现另外12例与慢性淋巴水肿相关的原发性皮肤淋巴瘤病例。慢性淋巴淤滞可能导致局部免疫系统功能障碍，从而易引发肿瘤形成，尤其是皮肤淋巴瘤。
