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印度哈里亚纳邦小反刍动物蓝舌病与小反刍兽疫病毒的混合感染。

Concurrent infection of Bluetongue and Peste-des-petits-ruminants virus in small ruminants in Haryana State of India.

机构信息

Department of Animal Biotechnology, College of Veterinary Sciences, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana, India.

Department of Veterinary Microbiology, College of Veterinary Sciences, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana, India.

出版信息

Transbound Emerg Dis. 2018 Feb;65(1):235-239. doi: 10.1111/tbed.12610. Epub 2017 Jan 24.

DOI:10.1111/tbed.12610
PMID:28116836
Abstract

Bluetongue (BT) and peste-des-petits-ruminants (PPR) are major transboundary diseases of small ruminant, which are endemic in India. Testing of bluetongue virus (BTV) and peste-des-petits-ruminants virus (PPRV) from recent outbreaks (2015-2016) in different regions of Haryana State of India revealed that 27.5% of the samples showed the presence of dual infection of BTV and PPRV. Analysis of Seg-2 of BTV (the serotype-determining protein) showed the presence of BTV-12w in several isolates. However, analysis of N gene fragment amplicons showed that viruses belong to lineage IV were most closely related to a pathogenic strain of PPRV from Delhi. This is the first report of co-circulation of PPRV lineage IV and bluetongue virus serotype 12 in the state.

摘要

蓝舌病(BT)和小反刍兽疫(PPR)是小反刍动物的主要跨境疾病,在印度流行。对印度哈里亚纳邦不同地区最近(2015-2016 年)暴发疫情的蓝舌病毒(BTV)和小反刍兽疫病毒(PPRV)的检测显示,27.5%的样本显示存在 BTV 和 PPRV 的双重感染。BTV Seg-2 的分析(血清型决定蛋白)显示,在几个分离株中存在 BTV-12w。然而,N 基因片段扩增子的分析表明,属于谱系 IV 的病毒与来自德里的致病性 PPRV 株最为密切相关。这是该州首次报告 PPRV 谱系 IV 和蓝舌病血清型 12 的共同流行。

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