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哌替啶作为静脉局部麻醉剂的应用。

Use of pethidine as an intravenous regional anesthetic.

作者信息

el-Bakry M S, el-Shafei S B, Seyam E M, el-Kobbia N M, Ebrahim U H

机构信息

Department of Anaesthesia, Faculty of Medicine, University of Alexandria, Egypt.

出版信息

Middle East J Anaesthesiol. 1989 Jun;10(2):189-94.

PMID:2811780
Abstract

Pethidine 100 mg in 30-40 ml saline was given in a group of patients by the conventional technique of intravenous regional anesthesia. Fourty percent of the patients did not feel any form of pain or discomfort, 26.7% experienced only vague sensations which did not call for additional drugs but 13.3% felt some form of pain or discomfort for which diazepam was given and was enough for surgery to be completed. In the rest of the patients (20%) there was intolerable pain for which patients were given general anesthesia. This last category was operated upon for recent fractures or digital conditions and it is known that intravenous regional anesthesia using conventional local anesthetics for such patients usually fails. In a control group in which 30-40 ml saline without pethidine were injected, there was complete failure of the technique.

摘要

一组患者采用传统静脉区域麻醉技术,给予100毫克哌替啶溶于30 - 40毫升生理盐水中。40%的患者未感到任何形式的疼痛或不适,26.7%仅经历模糊的感觉,无需额外用药,但13.3%感到某种形式的疼痛或不适,为此给予地西泮,且足以完成手术。其余患者(20%)存在难以忍受的疼痛,为此给予全身麻醉。最后这一类患者因近期骨折或手指疾病接受手术,众所周知,对这类患者使用传统局部麻醉药进行静脉区域麻醉通常会失败。在一个对照组中,注射30 - 40毫升不含哌替啶的生理盐水,该技术完全失败。

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