J Oral Facial Pain Headache. 2017;31(1):61-71. doi: 10.11607/ofph.1665.
To conduct a pilot trial to test the feasibility of a guided self-help intervention for chronic orofacial pain.
A pilot randomized controlled trial was conducted to compare the intervention with usual treatment. A total of 37 patients with chronic orofacial pain were randomized into either the intervention group (n = 19) or the usual treatment (control) group (n = 18). Validated outcome measures were used to measure the potential effectiveness of the intervention over a number of domains: physical and mental functioning (Short Form 36 [SF-36]); anxiety and depression (Hospital Anxiety and Depression Scale [HADS]); pain intensity and interference with life (Brief Pain Inventory [BPI]); disability (Manchester Orofacial Pain Disability Scale [MOPDS]); and illness behavior (Revised Illness Perceptions Questionnaire [IPQr]). Bootstrap confidence intervals were computed for the treatment effect (ES) posttreatment and at 3 months follow-up and adjusted for baseline values of the outcome measure by using analysis of covariance.
At posttreatment and the 3-month follow-up, 11 participants in the intervention group and 7 in the control group failed to complete outcome measures. The intervention was acceptable and could be feasibly delivered face to face or over the telephone. Although the pilot trial was not powered to draw conclusions about the effectiveness, it showed significant (P < .05) effects of the intervention on physical and mental functioning and treatment control.
The self-help intervention was acceptable to patients and allowed them to better understand and self-manage chronic orofacial pain. It showed potential effectiveness on outcome domains related to functioning and illness perception. Further research is needed to understand the cost effectiveness of the intervention for chronic orofacial pain.
进行一项试点试验，以测试针对慢性口腔颌面部疼痛的指导自助干预的可行性。
进行了一项试点随机对照试验，以比较该干预与常规治疗。共有 37 名慢性口腔颌面部疼痛患者被随机分为干预组（n = 19）或常规治疗（对照组）（n = 18）。使用经过验证的结果测量来衡量干预在多个领域的潜在效果：身体和精神功能（短格式 36 [SF-36]）；焦虑和抑郁（医院焦虑和抑郁量表 [HADS]）；疼痛强度和对生活的干扰（简明疼痛量表 [BPI]）；残疾（曼彻斯特口腔颌面部疼痛残疾量表 [MOPDS]）；和疾病行为（修订疾病认知问卷 [IPQr]）。Bootstrap 置信区间用于治疗效果（ES）的治疗后和 3 个月随访，并通过使用协方差分析调整结果测量的基线值进行调整。
在治疗后和 3 个月随访时，干预组有 11 名参与者和对照组有 7 名参与者未能完成结果测量。该干预措施是可以接受的，可以面对面或通过电话进行有效传递。尽管该试点试验没有足够的能力得出关于有效性的结论，但它显示出干预对身体和精神功能以及治疗控制的显著（P <.05）效果。
自助干预措施得到了患者的认可，使他们能够更好地理解和自我管理慢性口腔颌面部疼痛。它在与功能和疾病认知相关的结果领域显示出潜在的有效性。需要进一步的研究来了解该干预措施对慢性口腔颌面部疼痛的成本效益。
