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A Golden Age for Working with Public Proteomics Data.

作者信息

Martens Lennart, Vizcaíno Juan Antonio

机构信息

Medical Biotechnology Center, VIB, Ghent, Belgium; Department of Biochemistry, Ghent University, Ghent, Belgium; Bioinformatics Institute Ghent, Ghent University, Ghent, Belgium.

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

出版信息

Trends Biochem Sci. 2017 May;42(5):333-341. doi: 10.1016/j.tibs.2017.01.001. Epub 2017 Jan 22.


DOI:10.1016/j.tibs.2017.01.001
PMID:28118949
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5414595/
Abstract

Data sharing in mass spectrometry (MS)-based proteomics is becoming a common scientific practice, as is now common in the case of other, more mature 'omics' disciplines like genomics and transcriptomics. We want to highlight that this situation, unprecedented in the field, opens a plethora of opportunities for data scientists. First, we explain in some detail some of the work already achieved, such as systematic reanalysis efforts. We also explain existing applications of public proteomics data, such as proteogenomics and the creation of spectral libraries and spectral archives. Finally, we discuss the main existing challenges and mention the first attempts to combine public proteomics data with other types of omics data sets.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e27/5414595/f174cd5c9ac3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e27/5414595/f174cd5c9ac3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e27/5414595/f174cd5c9ac3/gr1.jpg

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本文引用的文献

[1]
Discovering and linking public omics data sets using the Omics Discovery Index.

Nat Biotechnol. 2017-5-9

[2]
The ProteomeXchange consortium in 2017: supporting the cultural change in proteomics public data deposition.

Nucleic Acids Res. 2017-1-4

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Demonstration of Protein-Based Human Identification Using the Hair Shaft Proteome.

PLoS One. 2016-9-7

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Cell. 2016-7-28

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