Zhou Thierry, Aptel Florent, Bron Alain M, Cornut Pierre-Loïc, Palombi Karine, Thuret Gilles, Rouberol Frédéric, Creuzot-Garcher Catherine, Chiquet Christophe
Grenoble Alpes University, Grenoble, France.
Department of Ophthalmology, University Hospital of Grenoble, Grenoble, France.
Br J Ophthalmol. 2017 Sep;101(9):1211-1216. doi: 10.1136/bjophthalmol-2016-309542. Epub 2017 Jan 24.
To analyse the macula imaged with optical coherence tomography (OCT) in patients treated for acute postcataract endophthalmitis.
Patients presenting with acute postcataract endophthalmitis were included in this observational and multicentre study from January 2008 to December 2011. We recorded the following OCT data at the 3, 6 and 12-month visits: the central macular thickness, the perifoveal macular thickness, the central foveal point thickness and abnormalities of the outer retina, the macula and vitreoretinal interface.
46 patients were included in the OCT analysis. From month 3 to 12, epiretinal membrane (ERM) prevalence increased from 26% to 39%, vitreomacular traction prevalence decreased from 12% to 6%, non-tractional macular oedema (ME) prevalence varied between 7% and 13%. Only macular thinning remained stable at 10%. At month 12, a significant correlation was found between non-tractional ME and capsular rupture (at the time of cataract extraction, p=0.03). Eyes with an ERM exhibited increased central macular thickness (p=0.001) and lower visual acuity (VA) (p=0.02) at M12 in comparison to the group with normal macula. OCT analysis showed a significant association between ERM and the alteration of the ellipsoid band (p=0.02), as well as the external limiting membrane (ELM, p=0.07) at M12.
ERM and ME were the main macular abnormalities diagnosed after 1 year of follow-up, associated with VA less than or equal to 20/40 in 50% of the cases. Ultrastructural abnormalities of the ELM and the ellipsoid band were frequently observed in those patients.
分析接受急性白内障后眼内炎治疗患者的光学相干断层扫描（OCT）黄斑成像。
2008年1月至2011年12月，本观察性多中心研究纳入了出现急性白内障后眼内炎的患者。我们在3个月、6个月和12个月随访时记录了以下OCT数据：中心黄斑厚度、黄斑中心凹周围厚度、中心凹点厚度以及外层视网膜、黄斑和玻璃体视网膜界面的异常情况。
46例患者纳入OCT分析。从3个月到12个月，视网膜前膜（ERM）患病率从26%增至39%，玻璃体黄斑牵引患病率从12%降至6%，非牵引性黄斑水肿（ME）患病率在7%至13%之间波动。只有黄斑变薄稳定在10%。在12个月时，发现非牵引性ME与囊膜破裂（白内障摘除时，p=0.03）之间存在显著相关性。与黄斑正常组相比，有ERM的眼睛在12个月时中心黄斑厚度增加（p=0.001），视力（VA）较低（p=0.02）。OCT分析显示，在12个月时，ERM与椭圆体带改变（p=0.02）以及外限制膜（ELM，p=0.07）之间存在显著关联。
ERM和ME是随访1年后诊断出的主要黄斑异常，50%的病例中视力小于或等于20/40。这些患者中经常观察到ELM和椭圆体带的超微结构异常。
