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乳腺钼靶筛查时的乳腺癌风险评估:高危女性的认知与临床管理结果

Breast Cancer Risk Assessment at the Time of Screening Mammography: Perceptions and Clinical Management Outcomes for Women at High Risk.

作者信息

Morman Nichole A, Byrne Lindsey, Collins Christy, Reynolds Kelly, Bell Jeffrey G

机构信息

OhioHealth Genetic Counseling Program, Bing Cancer Center, OhioHealth, Columbus, OH, 43214, USA.

OhioHealth Riverside Methodist Hospital, OhioHealth Research & Innovations Institute, Columbus, OH, USA.

出版信息

J Genet Couns. 2017 Aug;26(4):776-784. doi: 10.1007/s10897-016-0050-y. Epub 2017 Jan 26.

Abstract

The purpose of this study was to evaluate the utility of a breast cancer risk assessment (BCRA) at the time of screening mammogram. Women whose BCRA indicated a high risk for cancer received a letter with instructions for breast health care and genetic counseling if appropriate. After 6 months this group received surveys to evaluate their risk perception and their recall of, and compliance with, recommendations. We also explored the impact of other variables such as a recommendation for genetic counseling and physician communication with the women. After the BCRA, the majority of high risk women reported no change in their perceived risk of cancer. A woman's perceived risk of cancer after a BCRA was significantly associated with her recall of recommendations for breast health care, but not with compliance. A recommendation for genetic counseling was not significantly related to women's perceived risk of cancer after the BCRA. Ten percent of women who should have obtained genetic counseling actually completed an appointment. Women who discussed their BCRA results with their physicians were more compliant with a six month breast exam with a doctor (53% vs 17%, p = 0.018). Overall, women felt that the BCRA was helpful and did not cause undue stress or anxiety. Although the cohort's compliance with recommendations was suboptimal, physicians' interactions with their patients may have a positive influence on their compliance.

摘要

本研究的目的是评估在乳腺钼靶筛查时进行乳腺癌风险评估(BCRA)的效用。BCRA显示癌症高风险的女性会收到一封信,其中包含乳腺保健指导以及在适当时进行遗传咨询的说明。6个月后,该组接受调查以评估她们的风险认知以及对建议的回忆和遵循情况。我们还探讨了其他变量的影响,例如遗传咨询建议以及医生与女性的沟通情况。在进行BCRA后,大多数高风险女性表示她们感知到的癌症风险没有变化。BCRA后女性感知到的癌症风险与她对乳腺保健建议的回忆显著相关,但与遵循情况无关。遗传咨询建议与BCRA后女性感知到的癌症风险没有显著关联。应该接受遗传咨询的女性中有10%实际完成了预约。与医生讨论过BCRA结果的女性更有可能遵循与医生进行六个月一次乳腺检查的建议(53%对17%,p = 0.018)。总体而言,女性认为BCRA是有帮助的,并且不会造成过度的压力或焦虑。尽管该队列对建议的遵循情况并不理想,但医生与患者的互动可能会对她们的遵循情况产生积极影响。

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