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[左心室心肌梗死后室壁瘤的外科治疗。近期及远期结果]

[Surgical therapy of post-infarct aneurysm of the left ventricle. Immediate and long-term results].

作者信息

Barboso G, Fragnito C, Saccani S, Beghi C, Contini S A, Tagliavini S, Ghinelli L, Fesani F

出版信息

Minerva Cardioangiol. 1989 Jun;37(6):289-97.

PMID:2812446
Abstract

Between January 1982 and December 1986, 62 patients (59 male and 3 female) ranging in age from 37 to 69 years (mean 53) underwent resection of postinfarction left ventricular aneurysm. The indication for operation was angina in 23 cases (37%), congestive heart failure (CHF) in 7 (11.2%), angina and CHF in 29 (46.8%), rupture in 1; 2 patients were low symptomatic. Ventricular arrhythmias were present in 6 (9.7%) cases and previous systemic embolism in 4 (6.4%). Forty-seven (75.8%) patients had lesions of three coronary arteries with involvement of left main coronary artery in 4 cases; 10 (16.1%) had lesions of two vessels [left anterior descending (LAD) and/or right coronary artery]; 4 (6.4%) had only LAD artery involvement, and 1 had no significant coronary artery stenoses. Left ventricular ejection fraction (EF) was less than 0.30 in 22% of cases, between 0.30 and 0.40 in 25.4% and greater than 0.40 in 50%. The location of the aneurysm was anterolateral or apical (83.8%), posterior (14.5%) and lateral (1.6%). Left ventricular aneurysmectomy with myocardial revascularization was performed in 61 patients (bypass/patient = 2.7), with ventricular septoplasty in 20 and concomitant mitral valve replacement in 3 patients. LAD was grafted in 59.6% of anterior aneurysm. Operative mortality (30 days) was 4.8%, the late mortality, with a follow-up between 12 and 72 months (mean 38), was 6.7% and the actuarial 5 year survival rate was 85% (91% without operative mortality). In our experience, despite no evidence of any operative risk factors, no improvement was noted in radionuclide left ventricular ejection fraction in patients undergoing aneurysmectomy with ventricular septoplasty.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1982年1月至1986年12月期间,62例患者(59例男性,3例女性)接受了心肌梗死后左心室室壁瘤切除术,年龄在37至69岁之间(平均53岁)。手术指征为:23例(37%)为心绞痛,7例(11.2%)为充血性心力衰竭(CHF),29例(46.8%)为心绞痛合并CHF,1例为破裂;2例症状轻微。6例(9.7%)存在室性心律失常,4例(6.4%)既往有系统性栓塞史。47例(75.8%)患者三支冠状动脉有病变,其中4例累及左主冠状动脉;10例(16.1%)有两支血管病变[左前降支(LAD)和/或右冠状动脉];4例(6.4%)仅LAD动脉受累,1例无明显冠状动脉狭窄。22%的病例左心室射血分数(EF)小于0.30,25.4%在0.30至0.40之间,50%大于0.40。室壁瘤位于前外侧或心尖部(83.8%),后部(14.5%),外侧(1.6%)。61例患者(搭桥/患者=2.7)行左心室室壁瘤切除术并心肌血运重建,20例行心室间隔成形术,3例行同期二尖瓣置换术。59.6%的前壁室壁瘤移植了LAD。手术死亡率(30天)为4.8%,随访12至72个月(平均38个月)的晚期死亡率为6.7%,5年预期生存率为85%(无手术死亡者为91%)。根据我们的经验,尽管没有任何手术危险因素的证据,但接受室壁瘤切除术并心室间隔成形术的患者,放射性核素左心室射血分数未见改善。(摘要截选至250字)

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