Cooperman M, Stinson E B, Griepp R B, Shumway N E
J Thorac Cardiovasc Surg. 1975 Feb;69(2):321-8.
Operative and late postoperative results in 55 patients undergoing resection of a discrete, saccular type left ventricular aneurysm are described. All patients had occlusive lesions of either the left anterior descending or left main coronary artery, and 72 per cent had significant multivessel disease. Preoperative factors that correlated significantly with decreased long-term survival were age greater than 60 years, severe congestive heart failure, and subnormal cardiac output at rest. The primary determinant of long-term postoperative survival appears to be the functional state of residual myocardium after aneurysmectomy. The survival rate for patients with multivessel disease was not less than that of patients with isolated lesions of the left anterior descending coronary artery. The impact of simultaneous aorto-coronary bypass grafting on postoperative results in patients with multivessel coronary disease is discussed. An advantage to concomitant revascularization with aneurysmectomy cannot be statistically corroborated in this series. However, improvement in results since the routine application of bypass grafting in appropriate cases, the uniform operative survival of bypassed patients with triple vessel disease, and the relatively high frequency of myocardial infarction as a cause of late postoperative death suggest that bypass grafting in patients with multivessel disease should be combined with aneurysmectomy to maximally improve long-term prognosis.
本文描述了55例接受局限性囊状型左心室动脉瘤切除术患者的手术及术后晚期结果。所有患者均有左前降支或左主干冠状动脉闭塞性病变,72%有严重多支血管病变。与长期生存率降低显著相关的术前因素为年龄大于60岁、严重充血性心力衰竭和静息时心输出量低于正常。术后长期生存的主要决定因素似乎是动脉瘤切除术后残余心肌的功能状态。多支血管病变患者的生存率不低于左前降支冠状动脉孤立病变患者。讨论了同期主动脉-冠状动脉旁路移植术对多支冠状动脉疾病患者术后结果的影响。在本系列中,无法从统计学上证实动脉瘤切除术同期血运重建的优势。然而,自适当病例常规应用旁路移植术以来结果有所改善、三支血管病变旁路移植患者的手术生存率一致以及心肌梗死作为术后晚期死亡原因的相对高发生率表明,多支血管病变患者的旁路移植术应与动脉瘤切除术联合应用,以最大程度改善长期预后。